Lean By Design
Lean by Design explores how organizations can fix what’s predictably broken in their operations — starting with the systems, decisions, and behaviors that shape how work gets done. Hosts Oscar Gonzalez and Lawrence Wong speak with leaders from biopharma and beyond, drawing lessons from industries that share the same pursuit of clarity, efficiency, and sustainable execution. Each episode breaks down real challenges into practical insights that help teams align better, think smarter, and move faster. Produced by Sigma Lab Consulting, Lean by Design helps organizations design for what works—and eliminate what doesn’t. Listen on Spotify, Apple Podcasts, or wherever you get your podcasts.
Podcasting since 2022 • 31 episodes
Lean By Design
Latest Episodes
0209. Efficiency Is Not Just Cutting Costs
In this episode, we discuss the 2025 MassBio Industry Snapshot — an annual report tracking employment trends, investment, real estate, and pipeline activity across ...
•
51:19
0208. It’s Not the Science — It’s the System
Why Operational Excellence is Biopharma’s Next Competitive AdvantageIn this special cofounder episode of Lean by Design, Oscar Gonzalez and Lawrence Wong pull back the curtain on the ideas behind Oscar’s upcoming book—a...
•
Season 2
•
Episode 8
•
54:51
0207. Fix What Matters Most: Rethinking Workflow Improvement in Biopharma
In this episode, we introduce a new approach to operational excellence, one built for the realities of today’s biopharma landscape.As the industry faces tighter budgets and widespread restructuring, the pressure to “do more with less” ha...
•
Season 2
•
Episode 7
•
56:11
0206. From Chaos to Clarity: Bridging the Gap Between R&D Decisions and Scientific Data with Bogdan Knezevic
In this episode, we sit down with Bogdan Knezevic, co-founder and CEO of Kaleidoscope, to talk about a growing challenge in life sciences R&D: making smart decisions when data is scattered across teams, tools, and partners.Bogdan exp...
•
Season 2
•
Episode 6
•
51:06
0205. Before You Scale: Designing Workflows That Set Teams Up for Success with David Hirschfeld
In this episode, we sit down with David Hirschfeld, 35-year software veteran and founder of Tekyz, to talk about why designing workflows before you start building is critical for sustainable growth.We explore how the speed of mo...
•
Season 2
•
Episode 5
•
43:05