Lean By Design
Lean by Design explores how organizations can fix what’s predictably broken in their operations — starting with the systems, decisions, and behaviors that shape how work gets done. Hosts Oscar Gonzalez and Lawrence Wong speak with leaders from biopharma and beyond, drawing lessons from industries that share the same pursuit of clarity, efficiency, and sustainable execution. Each episode breaks down real challenges into practical insights that help teams align better, think smarter, and move faster. Produced by Sigma Lab Consulting, Lean by Design helps organizations design for what works—and eliminate what doesn’t. Listen on Spotify, Apple Podcasts, or wherever you get your podcasts.
Lean By Design
Latest Episodes
0311. Everything is On Fire And Somehow That Is Normal
We pull an excerpt from Oscar’s book Predictably Broken and ask the question so many biopharma teams avoid: if the work feels broken, why doesn’t anyone fix it. We argue the issue isn’t apathy or ignorance, but the real weight of diagnosing roo...
0310. The Slow Leak Dismantling Your Operations
A tiny stain on a garage ceiling doesn’t feel like a big deal until it comes back, darker, wider, and harder to ignore. That’s the exact pattern we see in operational dysfunction: the real problem isn’t loud, it doesn’t send alerts, and it rare...
0309. A Farewell. Founders At The Fork In The Road
The origin story of a business is rarely clean, and it’s almost never convenient. Oscar and Lawrence sit down for a candid, unscripted conversation. We look back on how their partnership started in grad school right as COVID pushed everyt...
0308. The Space Between Systems
Nobody sets out to build a broken system. Every tool your organization is running was the right call the day it was purchased. Someone fought for the budget, ran the validation, and trained the team. And they were right.But the work stil...
0307. Aligned at the Top, Lost at the Bottom
Most organizations believe they have alignment. The strategy is written, the leadership team is on the same page, and everyone knows the goal. But what happens on Monday morning, when the teams spread out and the work actually begins?In ...