The Fueled & Free Podcast

68. Microdosing GLP-1s / Semaglutides: A Tool For Reducing Inflammation, Weight Loss, & Insulin Resistance

Margaret Powell Season 4

Today’s episode topic is a LONG time coming, and it’s something that is both intriguing + triggering: GLP1’s and semaglutide peptides. 


I know there are sooo many strong opinions about GLP-1s (especially in the holistic health space). My goal is to bring a fresh perspective to these medications - specifically, as to how they can impact women’s metabolic health in a positive way, whether you’re dealing with PCOS, insulin resistance or in perimenopause.


I’m diving into the nitty gritty on GLP-1s peptides & how they *actually* work, and the concept of microdosing GLP-1s. I’m also discussing naturally-occurring GLP-1s vs. medications like semaglutide and tirzepatide, how peptides positively affect inflammation, insulin resistance during perimenopause, common myths and ‘fear mongering’ surrounding GLP-1s, and more.


If you’ve ever felt torn about GLP-1 medications, you’re NOT alone. It’s important to realize that these aren’t just another ‘quick fix’, and personalization is key here!


If you’re struggling with the unique metabolic storm that is perimenopause, learn more about how our team can help you HERE. We would love to support you with your metabolic and hormone health so you can heal + THRIVE in your everyday life!


Episode Recap:

  • Understanding GLP-1s + how they work {4:22}
  • ‘Naturally’ occurring GLP-1s vs. prescription GLP-1s {6:20}
  • Factors that contribute to lowering your body’s natural GLP-1 {9:01}
  • Supporting & boosting your body’s natural GLP-1 production {13:03}
  • Why GLP-1s can be key in perimenopause + how these can support insulin resistance and lowering inflammation {16:14}
  • Common myths & fears surrounding GLP-1s {18:17}
  • Microdosing GLP-1s + how we’ve supported clients in this process {24:55}
  • Why microdosing GLP-1s can support hormonal & metabolic shifts during perimenopause {35:38}
  • Why GLP-1s aren’t a one-size-fits-all & personalization matters {39:44}
  • Options for getting GLP-1s prescribed for you {43:36}



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**Disclaimer: The information shared in this podcast is NOT meant to be taken as individual or medical advice. Please seek the advice of your physician or healthcare provider regarding any medical condition or treatment.