The Plus SideZ: Cracking the Obesity Code

Perimenopause, Menopause, HRT & GLP1s Explained with Dr. Cathleen Brown Part 1

Season 5 Episode 5

Resources for the Community:

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https://linktr.ee/theplussidezpodcast 

Ro - Telehealth for GLP1 weight management 

https://ro.co/weight-loss/?utm_source=plussidez&utm_medium=partnership&utm_campaign=comms_yt&utm_content=45497&utm_term=55


Start your perimenopause HRT journey with Winona  https://winona.pxf.io/gOLeV0

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Part 1
Let’s talk about the change. Chances are, it’s already happening, and nobody handed you a guidebook.

In this episode, we sit down with Dr. Cathleen Brown, Medical Director at Winona, to finally demystify perimenopause and menopause. We’re bringing this conversation to our audience because so many people on a GLP-1 journey are also navigating hormonal shifts. Whether it’s perimenopause, menopause, or just the hormonal chaos of midlife, these changes can impact everything—from weight and sleep to mood and metabolism.

We’re here to break it all down.

From night sweats and mood swings to insulin resistance and hormone shifts, we cover it all with real talk and science-backed solutions. Dr. Brown walks us through the current landscape of hormone replacement therapy (HRT), including estrogen, progesterone, testosterone, and even Osphena. She also addresses the past fears about HRT—strokes, heart attacks, cancer—and how updated research is changing the conversation around safety, longevity, and quality of life.

We also explore the role of GLP-1 medications in the menopause space, especially for those with PCOS, insulin resistance, or other metabolic challenges. Could these meds be part of a modern menopause toolkit? Dr. Brown shares her perspective.

And yes, we get personal too. As Winona patients ourselves, we’re sharing what’s worked, what hasn’t, and what questions we had going in—so you don’t have to figure it all out alone.

What you’ll hear in this episode:

  • What perimenopause and menopause actually are (and why it matters)
  • Why hormone disruptions are common during the GLP-1 journey
  • GLP-1s and menopause: emerging research and real-world use
  • HRT today: what’s changed, what’s safer, and what’s working
  • Testosterone, Osphena, and how to treat painful sex
  • Habits that actually help during the hormonal rollercoaster

If you’ve ever felt confused, dismissed, or overwhelmed by menopause, you’re not alon

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