Clearly Hormonal
Have you ever wondered why your body feels like it's falling apart just as you're hitting your stride in other areas of your life? Join Dr. Komal Patil-Sisodia as she explores women’s metabolic health changes that start in perimenopause. The episodes center around educating and empowering women to have open dialogue with their doctors so that they can achieve their best metabolic health. Dr. Patil-Sisodia is board certified in Endocrinology, Obesity Medicine and Internal Medicine. She is also a Menopause Society Certified Practitioner. Any medical discussion on this podcast is purely for educational purposes and is not individualized medical advice. Please consult with your doctor to discuss any health concerns you may have.
Episodes
62 episodes
Beyond the Buzz: Where GLP-1s Really Fit in PMOS Care
Dr. Komal Patil-Sisodia continues the PMOS Awareness Month series by walking through where GLP-1 medications, like semaglutide and tirzepatide, fit into PMOS treatment. She explains what GLP-1s actually do in the body, who is likely to benefit,...
Lean PMOS: Why the Diagnosis Gets Missed Without Weight Gain
Many people picture PMOS (polyendocrine metabolic ovarian syndrome, formerly known as PCOS) as a condition tied to weight gain. But the diagnostic criteria never mention body size at all, and a significant number of people with PMOS have a comp...
PMOS After the Reproductive Years: Why It Doesn't Go Away
PMOS Awareness Month kicks off with a reframe: PMOS is not a condition that resolves once your cycles regulate or once you're done having kids. It is a lifelong cardiometabolic condition that happens to announce itself first through reproductiv...
Equality & the Executive Suite: The Menopause Penalty Revisited
On Women's Equality Day, host Dr. Komal Patil-Sisodia revisits an idea from an early episode of Clearly Hormonal: the menopause penalty, the disproportionate income loss, leadership attrition, and career disruption that midlife women face. This...
Same Diagnosis, Different Bodies: The Four PMOS Phenotypes
Two women get the same diagnosis, PMOS (formerly known as PCOS), and end up with completely different symptoms. One has irregular periods, acne, and high androgens. The other has none of that, just an ultrasound finding. How can that be the sam...
Perimenopause or Something Else? Bringing Nuance Back to Midlife Symptoms
Perimenopause is having a cultural moment, and endocrinologist Dr. Komal Patil-Sisodia is glad it is, but in this launch episode of Clearly Hormonal, she pushes back on social media's habit of attributing nearly any midlife symptom to hormones....
Peptides: Evidence-Based Medicine vs. Social Media Hype
Endocrinologist Dr. Komal Patil-Sisodia defines peptides as short amino-acid chains (with examples like insulin) and notes that any package or claim stating “contains peptides” is meaningless without knowing which peptide, how it was tested, an...
The Peptide Vote: What the FDA's Advisors Just Recommended
Dr. Komal Patil-Sisodia explains that headlines claiming “FDA approves peptides” are misleading: an FDA advisory committee narrowly voted to recommend adding six peptides (BPC-157, TB-500, KPV, MOTS-c, Epitalon, Semax) to a compounding list, a ...
The Biggest Myths About Type 1 Diabetes (and the Truth Behind Them)
Type 1 diabetes isn't just a childhood disease, and it isn't caused by sugar, weight, or lifestyle. In this episode, Dr. Komal Patil-Sisodia breaks down why type 1 diabetes is so often missed in adults, especially in people mislabeled as type 2...
Type 2 Diabetes Isn't a Moral Failing: Genetics, Hormones, Stigma, and the Truth About Insulin
Type 2 Diabetes Isn't a Moral Failing: Genetics, Hormones, Stigma, and the Truth About InsulinIf you've ever been told — or told yourself — that your type 2 diabetes is something you caused and something you could fix if you j...
Thyroid Myth Busting (Part 2): What Actually Helps and What Doesn't
Getting diagnosed with Hashimoto's can feel overwhelming, especially after spending five minutes online. Suddenly you're told to eliminate gluten, avoid broccoli, stop eating soy, buy expensive supplements, and ask your doctor for desiccated th...
Think It's Your Thyroid? Midlife Fatigue, Weight Gain, and the Myths Behind "Normal" Labs
One in four women will have some degree of thyroid dysfunction after menopause — so it's not unreasonable to test it. But Dr. Komal Patil-Sisodia says the real problem isn't whether we test, it's what we do (or don't do) after the results come ...
Spit Happens: The Truth About Cortisol Testing
Picture three women. One is spitting into four little tubes throughout the day, mailing them off to a lab, hoping to finally get answers about her "adrenal fatigue." Another has been on a steroid inhaler for years, or just got a cortisone shot ...
6 Adrenal Myths: Why “Adrenal Fatigue” Isn’t Real and What Actually Matters
“My adrenals are shot.” If you’ve said some version of that sentence this year, Dr. Komal Patil-Sisodia believes that you feel terrible—she just wants you to know that adrenal fatigue isn’t a real diagnosis, a lab value, or something your adren...
When the Room Goes Quiet: Scientific Integrity, Political Pressure, & What Was Lost at the ADA Conference
Dr. Komal Patil-Sisodia records live from her hotel room on the final night of the ADA 86th Annual Scientific Sessions in New Orleans — still processing what she witnessed earlier that week. The NIH director didn't show up to his own keynote. A...
PCOS is Now PMOS: What the Name Change Means for Every Era of Your Hormonal Life
On May 12, 2026, The Lancet published the results of a 14-year global effort: Polycystic Ovarian Syndrome (PCOS) has been officially renamed Polyendocrine Metabolic Ovarian Syndrome (PMOS). For over 170 million women worldwide — most of whom ha...
Decoding the Risk: What New Cholesterol Guidelines Mean for Women with Dr. Harpreet Tsui
The number-one cause of death in women is still heart disease — and perimenopause is where your cardiovascular risk starts to quietly climb. This week, Dr. Komal sits down with Dr. Harpreet Tsui, an internist, obesity medicine specialist, and f...
Why Women’s Heart Disease Gets Missed with Dr. Ambreen Mohamed
Heart disease has long been framed as a “man’s disease” – but women are being missed, misdiagnosed, and overlooked in ways that can be life-threatening, especially within South Asian communities where cardiovascular risk often develops earlier ...
Dismissed & Confused: Why Women Stop Trusting Their Bodies
Between trackers, lab tests, supplements, hormone experts, social media, and podcasts, women have more access to health information than ever before. However, despite (and sometimes because) of these resources, many women end up feelin...
Are You Ready For It? The Eras Tour of a Woman's Life
When it comes to hormonal health, women just aren’t set up for success. Unexpected physical symptoms and psychological side effects – combined with a lack of medical clarity and resources – can lead to overwhelming confusion and self-doubt.&nbs...
From Reset to Clarity: Why “Clearly Hormonal” Was Born
Do you ever feel like you’re not getting straight answers about your hormones, your cycle, or your health? You’re not alone. Women’s health has historically been under researched, undervalued, and under resourced, leaving many women stuck navig...
Ep 41: Pregnancy to Perimenopause with Dr. Emmie Strassberg
In this episode of Reset Recharge, host Dr. Komal Patil-Sisodia delves into the complexities of women's reproductive health with guest Dr. Emmie Strassberg, a maternal fetal medicine specialist. They discuss the challenges women face during pre...
Ep 40: When Menopause Sends You to the ER with Dr. Jessica Yearwood
In this episode of 'Reset Recharge,' host Dr. Komal Patil-Sisodia, a triple board certified endocrinologist, interviews Dr. Jessica Yearwood, a Menopause Society certified practitioner, about the deep impacts of perimenopause and menopause on w...
Ep 39: Midlife in the Middle: Caregiving & Burnout
In this episode of Reset Recharge, host Dr. Komal Patil-Sisodia discusses her personal experiences and insights into managing medical crises for loved ones while emphasizing the importance of self-care. She shares practical strategies for organ...
Ep 38: Mother Nature Is a Feminist
In this episode of 'Reset Recharge,' host Dr. Komal Patil-Sisodia, a triple board-certified endocrinologist and women's health expert, discusses the transformative journey of women's lives through various stages like puberty, reproductive years...