Rev Up Health

Type 3 Diabetes? The Surprising Connection Between Insulin Resistance and Alzheimer’s Risk

Dr. Mark and Tandi Hechler

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0:00 | 35:18

Dementia isn't just an "old age" problem—it’s a lifestyle and metabolic process that can begin in your 30s. In this episode of the RevUp Health Podcast, Dr. Mark and Tandi Hechler reveal why Alzheimer’s is increasingly called "Type 3 Diabetes" and how your daily habits in your 40s and 50s determine your cognitive future.

They break down the powerful connection between insulin resistance, neuroinflammation, and brain health. You’ll learn about the neuroprotective roles of estrogen and testosterone, the "brain fertilizer" effect of movement, and why your APOE4 status is a genetic predisposition, not a destiny.


What You’ll Learn:

  • The Metabolic Link: Why tracking Homa-IR and fasting insulin is the best way to predict cognitive risk.
  • Hormones & Cognition: How estrogen clears amyloid plaques and why hormone optimization is a key pillar of prevention.
  • The Power of Movement: Why strength training and aerobic exercise are the most effective ways to boost BDNF (Brain-Derived Neurotrophic Factor).
  • The Glymphatic "Reboot": How quality sleep acts as a garbage disposal for the brain, flushing out neurotoxic waste.
  • Lifestyle Levers: Practical steps to implement the "Revive" phase through social connection, nutrition, and targeted supplements like Magnesium Threonate.

Don't just save for retirement—invest in the cognitive health that allows you to enjoy it. Listen and subscribe to RevUp Health to learn how to keep your brain sharp and functional for decades to come.



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