GLP-1 Hub: Support, Community, and Weight Loss
Join Ana Reisdorf, dietitian and GLP-1 user, where science meets support, and your weight loss journey is backed by a community that gets it. Whether you're new to GLP-1 medications like Zepbound, Wegovy, Mounjaro or Ozempic, or just looking to optimize your results, this podcast is your trusted space for expert insights, real success stories, and practical strategies to help you feel your best.
GLP-1 Hub: Support, Community, and Weight Loss
Can Your Natural Hunger Hormones Help After GLP-1s? w/ Sarah Kennedy
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What happens to hunger and food noise when someone lowers their GLP-1 dose or stops taking the medication?
In this episode, Ana Reisdorf talks with Calocurb founder and CEO Sarah Kennedy about a unique supplement designed to support appetite regulation by stimulating the body’s natural satiety hormones.
Sarah walks through the reported results of a 24-week clinical trial involving 150 adults. She says the Calocurb group averaged 5.4% weight loss, reduced fat and visceral fat, and maintained skeletal muscle. Ana asks how the study was conducted, how hunger and cravings were measured, what side effects users may experience, and what evidence currently exists for using Calocurb alongside or after GLP-1 medication.
**IN THIS EPISODE**
- How Calocurb was developed from a New Zealand research initiative
- What the new 24-week clinical trial measured and reported
- How researchers measured hunger and food cravings
- The roles of CCK, GLP-1, and PYY in appetite regulation
- When and how Calocurb is designed to be taken
- Possible digestive side effects and the onboarding process
- Where Calocurb might fit alongside or after GLP-1 medication
- What research is still needed for people reducing or stopping GLP-1s
- Potential future studies involving postmenopausal women and adolescents
- Why Sarah describes Calocurb as a tool rather than a magic pill
**ABOUT THE GUEST**
Sarah Kennedy is the founder and CEO of Calocurb, a veterinarian by training, and an experienced nutrition and health-industry executive. During more than 20 years in dietary and animal nutrition, she led Healtheries/Vitaco New Zealand and held senior international and nutrition leadership positions at Fonterra. She is also an MIT Sloan Fellow in Global Leadership and Innovation and has served on the boards of government, private, philanthropic, and publicly listed organizations.
**CONNECT WITH SARAH AND CALOCURB**
Website:
https://calocurb.com
Instagram:
https://www.instagram.com/calocurb
YouTube:
https://www.youtube.com/@calocurb
**SPONSORS**
Johnson Fitness and Wellness offers home fitness equipment, expert guidance, delivery, and professional installation. Shop online and use code GLP1Hub5 for an exclusive offer:
https://www.johnsonfitness.com
Tyde Wellness provides clinician-guided GLP-1 care, nutrition support, hormone therapy, and longevity services. Use code GLP1Hub50 for $50 off your first month:
https://tydewellness.com/GLP1Hub
**CHAPTERS**
00:00 Why reducing calories can increase hunger
00:25 What happens when GLP-1 treatment changes?
01:34 Meet Sarah Kennedy
02:07 How CaloCurb was developed
05:20 What the 24-week trial reported
07:30 Trial design and lifestyle support
09:09 How hunger and cravings were measured
11:16 CCK, GLP-1, and PYY explained
13:16 When and how CaloCurb is used
16:47 Could it fit alongside or after GLP-1s?
19:02 Appetite regulation and weight maintenance
22:12 Side effects and the onboarding process
24:39 Combining CaloCurb with GLP-1 medication
26:33 Future studies and unanswered questions
29:48 Studying appetite support in adolescents
31:11 A tool, not a magic pill
33:59 Where to learn more
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*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.
Our vision was was never about weight loss. It was always to modernize human consumption. So what that means is our appetite center is in our hind brain, our primitive brain, which was amazing during evolution. But in a modern world it's not so helpful because if you drop your calories, your hunger will double.
SPEAKER_01What happens to hunger and food noise when someone reduces or stops their GLP1 medication? For many people, maintaining their progress can become more difficult when the dosage changes or the treatment ends. And that's created a lot of interest in other tools that might help support your appetite regulation beyond or maybe even in support of GLP1s. Welcome to the GLP1 Hub Podcast. I'm Anna Reisdorf, registered dietitian and GLP1 user. And today I'm joined again by Sarah Kennedy, founder and CEO of Callocurb, a unique dietary supplement designed to control hunger. Sarah is here to discuss a new 24-week clinical trial that examined weight loss, fat mass, skeletal muscles, hunger, and cravings. We talk about the unique story of how Call Curb came to be, what their extensive trial actually found, and what evidence does and does not yet exist for people taking or transitioning off medications. And I want to thank CaloCurb for sponsoring this episode. Now let's get into it. Awesome episode the first time.
SPEAKER_00Great. Thanks, Anna. Hi. I'm Sarah Kennedy. I'm the founder and CEO of Callicurb. And you're right, if I sound funny, uh it's a New Zealand accent. Don't tell it, don't say I'm Australian. It's New Zealand.
SPEAKER_01Very, very important. So tell us a little bit about your background and how you got involved with Callicurb.
SPEAKER_00Uh so Calicurb, um, let's just go back. Calicurb is 16 years and 30 million in funding. It was actually developed by the New Zealand government. Uh they started in about 2009, uh, because we have an obesity problem in New Zealand, just like everyone else around the world. So they started this, and what they were looking for was um a natural plant-based extract that would suppress appetite. And the reasons for that were that um that it was some partly historical. In the times of famine, uh people, Scottish people chewed very, very bitter heath berries to suppress their appetite. Also, um tribesmen in the Kalahari Desert chew very, very bitter cacti to suppress their appetite. That was actually the origin of Hoodia. And so there was these historical reasons, and um, and then there was some recent work they'd done on um mice. So uh interesting enough, they look a massive process. They went through, as I said, 16 years, but they they got the outstanding extract that they called Marisate, uh, which um is a very is an extract of hops, and the way we encapsulate it in calico is in these delayed release functions, which go down and dissolve in the uh upper gut to stimulate the release of your own, your endogenous or your natural appetite suppressing hormones, that being CCK. So we don't hear about that so often, but that is a very potent appetite suppressing hormone. GLP1, we've all heard of GLP1, and then lastly, PYY, which is also an appetite suppressing hormone. But I'll bring these up again when we talk about the fourth human clinical, because CCK and PYY are important. So just in a really, I'm just gonna whiz through 16 years, uh, outstanding extract that stimulated these. The first three human clinical trials showed that we uh decrease hunger by 30%, cravings by 40%, and an average calorie intake of 18%. Now, I think I gave you the comparison before, a semiglutide, so like a wagove is usually about 24%, right? So remember a GLP1 injectable is a synthetic hormone, we stimulate your own hormones. So quite different. Well, we are different. We are super stimulating your own endogenous. So that's sort of the the three human clinicals. Uh, but when I spoke to you, I think last time, we were just completing our fourth human clinical. So we knew we know we suppress appetite, we know we reduce calorie intake. But would this go into long-term weight loss? We knew that anecdotally, but of course, you know, we needed the clinical. So this was the fourth human clinical, which was 150 patients, men and women, a BMI between 25 and 35 over six months. And they were on treatment and non-treatment, so placebo and treatment over six months. Uh, they were seen monthly uh for body measurement. Uh so the drum roll, uh just an amazing result. Um yay, it was uh just published 10 days ago in Obesity Pillars, which is the journal of um uh um the American Obesity Medicine Association. Uh so just published. So what it showed was uh it was 5.4% weight loss, but it was all fat and no muscle. So that is extraordinary. So all fat. And what was really good about that, um, it was proportional to the visceral fat. So uh if you want to put it in terms, they lost around 10 pounds or 10.4 pounds over that time, uh, but it was all fat, no muscle, and proportional to visceral. So they lost three and a half times more visceral fat than um than the than the non-treatment group or placebo group, uh uh six times more fat. Uh uh, yeah, but no muscle. So we're really delighted, um, as you know, the reason being is that you can on the synthetic or the prescriptions lose up to 40% muscle. So uh you want a comparison? So interesting, published almost two weeks before us, was a 24-week observational trial using injectables, semaglutide and trisepatite. Uh when you adjust that for muscle loss, they lost 14 pounds, we lost 10 and a half. So, you know, there's three and a half pounds different. So, yeah, that's a fourth human clinical. Uh sounds easy, but it was three years in the making uh and two million dollars.
SPEAKER_01Yes. So um there's so much to unpack on this particular clinical. So the people were on it for a period of time. Now, did they receive any like counseling or support for like how to change their diet or anything like that, or they just were given this and nothing else?
SPEAKER_00No, they were well, it was a real world. We would call it a real world, but they were seen once a month. They were obviously seen once a month for measurements. Um and they were, it was uh they saw a dietitian then. And they were advised, it was very light touch, but they were advised to increase protein in their diet and to get moderate exercise. So yes, but that was once a month. So it certainly wasn't what I would call an intensive or an interventionist um lifestyle change.
SPEAKER_01Right. And the placebo group received that same information?
SPEAKER_00Absolutely same information. And it's fascinating watching the placebo group if you look at the graphs, um, because for the first couple of months they do lose a little bit of weight, not not anywhere as enough of as calicurb, um, because you know, there is, they are watching what they ate, but then of course it it bounces back up. So they lost, well, they lost nothing. So you'd be pissed off if you were in the placebo group, wouldn't you? Um but that's clinical trials. The other thing is we had a lot of measures all the way through there, and we significantly reduced hunger and craving during um so this of course makes it easier to follow lifestyle choices.
SPEAKER_01Sure. So how do you measure like hunger and cravings? Because when people take a GLP1, they automatically say, I don't think about food all day. So how do you like measure that in a clinical way?
SPEAKER_00Is it just self-reported? It's done by what's called a visual analog scale. Um, so it's a it's a questionnaire, um, and and that's it's clinically proven. I mean, that's what they used because you're right, how do you do it? So it's a visual analog scale, and it richly says, you know, how hungry are you? And you know, it's a scale, and you go, I'm not hungry, to I'm the hungriest I've ever been. So that's how they do it. And of course, from our third human clinical that we did, well, second and third that we did in male and female, we showed that in the last eight hours of a 24-hour water-only fast, we reduced uh female uh hunger by 100%, males by 80%. So we know we well, of course, because we are we are super stimulating these appetite suppressing hormones, which your own, which are telling you your brain. But the interesting thing is, you know how I said it was three? It's a CCK, GLP1, PYY. Well, that's really the interesting because CCK uh is known to metabolize fat and certainly visceral fat. So not only is it an appetite suppressing hormone, it's metabolizing fat. GLP1, we know is you know, your your appetite suppressing hormone, but PYY, which is the latter one which is further down in your intestinal tract, that is known to stimulate muscle stem cells or muscle satellite cells. So this is why we believe you've got the fat loss, accelerated fat loss, but no muscle. So it's this wonderful triple hormone um sciate, these triple satiety hormones, which are working to obviously help you lose weight, but it's the fat, not the muscle.
SPEAKER_01So, because the GLP1, even the the double agonist wouldn't target the PYY and the CCK, right?
SPEAKER_00No, they don't. No, no. And of course, we're stim we're stimul I mean, Wagovy or a semaglutide is just GLP1, a trzeptide is GLP1 and uh GIP. So you've got two hormones, one hormone, two, we're three hormones. Uh and you know, and as I said, we're uh as you know with a synthetic, they've mimicked, what they've done is they've mimicked your own natural GLP1, but they've changed a small molecule in it. So it lasts for seven days, not for um, not like Calicobe is four to six hours. And people will often say, well, how is that possible? Because your own natural GLP1 is broken down in like one to two minutes. And the point is that Calicobe goes down. I often try to equate it to like a pinball machine. It goes down the gastrointestinal tract and it's hitting these receptors as it goes down, firing off um these appetite suppressing hormones as it goes down. So, yeah, so it's um four to six hours is the the length of time at work. So, no, it's not seven days, but we say you do take it when you need it, which is, you know, when you're going to eat. So, you know, the golden rule with Kale curve is always take it uh an hour or an hour and a half, it doesn't really matter, um, before a meal, uh, and make sure your stomach is empty or semi-empty, because what you're trying to do is get it past the stomach into the upper intestine and have it with a glass of water just to help it on its way. So, um, and you know, do it before lunch, do it before dinner, or choose how you want to do it. Um, so yeah, that's sort of I was so it's so thrilled with the result. I I literally couldn't believe them when I saw them.
SPEAKER_01I know, I bet. You're very excited. Um, so with the cali curb, could this be something that you use just like for a meal that you maybe feel is more difficult, you know, like like dinner or like or do you have to do it three times a day?
SPEAKER_00No, no, absolutely. The wonderful thing about cali curb is you can come in and out of it. You know, it lasts for four to six hours and it's degraded out of your body within twenty hours. So, you know, 100% natural. And like I take mine, I probably take them uh I take mine in the morning because I intermittent fast, and it just means it takes away that food noise so I can get to twelve or one o'clock with I can walk past those muffins, I can do all of that without f thinking about it. Uh so I do that. But interesting as you said, like when I'll take it in the evening is if I'm going out for a a business dinner. And say I'm going out later, and I know we're not going to eat till about 7.38. And, you know, I haven't eaten since twelve. So, you know, of course, so I don't want to just dive into the bread basket. You know, I want to I want to eat, but I just don't want to eat as much. Uh so yeah, I'll take mine at probably five o'clock or six o'clock, something like that. So you can this is a wonderful thing. You can come in and out of it. You still want to eat, you just won't eat as much. We've just signalled your brain that you're full, so you will eat 20% less. So just think about cutting out, you know, quarter of your plate, and you'll suddenly go, ooh. You know how 45 minutes later, after a big meal, you go, ooh, you know, I'm really full. Well, we're just making you feel that faster, and you'll be and you'll be like, ooh, I can't, no, I don't want any more. And I was the worst packer of all, and now it's great I can finish a meal and go, oh, I'm good. You know, and I don't know if your mother always told you, you know, finish what's on your plate, which is not great advice because children are very receptive to when they're full, and that's because they've got a very good gut brain access. And um, don't finish your meal and say, your body is telling you you're full.
SPEAKER_01If you're on a GLP1 journey like I am, you've probably heard how important strength training is for maintaining muscle and supporting long-term health. But figuring out what equipment is right for your home can be overwhelming. That's why I recommend Johnson Fitness and Wellness as the largest specialty fitness retailer in the country with nearly 100 stores nationwide and online. They offer an incredible selection of strength equipment, treadmills, exercise bikes, ellipticals, and massage chairs. You'll find many of the fitness industry's most trusted brands, including Nike Strength, Force USA, Tonal, Matrix, and Peloton all in one place. And what I love the most is that you're not left to figure it out on your own. Their knowledgeable fitness experts take the time to understand your goals, your space, and your budget, helping you choose equipment that's right for you. They even offer white glove delivery and professional installation, making the whole process simple from start to finish. Visit your local Johnson Fitness and Wellness store or shop online at JohnsonFitness.com and use the code GLP1Hub5 for an exclusive offer for just my GLP1 Hub listeners. Yep, definitely. So how is this applied to somebody on GLP1? Because I've I see a few use cases for it. Either it could be a way to transition, lower your dose a little bit as you get to your maintenance, and then add this on for those situations like you mentioned, or maybe just have it be like something they could transition on completely. Where do you think it fits into the whole GLP one category? Because I know my people are stressed about regaining weight.
SPEAKER_00That is a great question. And what I'll tell you is when you're coming off your GLP one um medication, I always say it's not an if, it's a must. Right? You're coming off. And of course, what most people don't realize is you've depressed, you've suppressed your own natural hormones to zero. This is all published, all the rest, you've suppressed it to zero. So of course, when you come off them, and that'll take, depending on how long you've been on, that may take to four weeks, it may take eight weeks, it may take twelve weeks to get that natural to restart or reboot that gut brain access. And that's why people get this intense hunger. I'm not sure if your patients have talked to you about it, but they come off and they're like, I just want to eat. And that's because you don't have those natural hormones. So if you're taking calico, we are rebooting that gut brain access. So the advice I always say is you're titrating down in that last month, start taking calico there, and you're sort of building up your natural again as you're coming off the synthetic. And stay on it for at least three to four months, and then use it intermittently after that. If you know you're gonna be it's gonna be a difficult meal, you're going on holiday, you're going on a cruise, you're doing something like that. Use it like that, but definitely when you're coming off, uh, use it to kick start uh your own gut brain access.
SPEAKER_01Another abuse case that I see is is even just for people who might be already a normal weight but want to just maintain, right? All of us ladies getting older in age, those pounds tend to creep up. So this might be a tool for that sort of time. What do you think about that?
SPEAKER_00Absolutely love it. Our vision was was never about weight loss, it was always to modernize human consumption. So what that means is our appetite center is in our hind brain, our priv primitive brain, which was amazing during evolution. But in a modern world, it's not so helpful because if you drop your calories, your hunger will double. You know, your hunger is just driving you because it's a hind brain. So, and of course, in the modern world, we're surrounded by food and great food. It smells, it looks nice, and it's deliberately, you know, it's deliberately so it tastes good. So absolutely to modernize human consumption. So you can uh yeah, just eat less. So absolutely, is to help us in everyday life. And, you know, I think I've said it to you before. We used to say gin was mummy's little helper. I think Calicurb is mummy's little helper because, you know, it helps in everyday life. Like I'm not looking to lose weight, uh, I'm just looking to help me in everyday life. And I think I told you before what I love is um, you know, and every founder has a story, but I had a love-hate relationship with food my whole life. And I was on my first diet at 11. So many of you people listening would know that love-hate. I love it, but I hate it. I eat too much and I hate it. And I can quite honestly say to you, I'm at peace with food now. Uh and the other thing, you know, people say is, well, do I have to be on Callicurb for life? Well, the interesting thing is we upregulate your receptors, we don't downregulate. So I kind of think of these little receptors in your L cells that we're exercising them. We're not suppressing them, we're exercising them. So um, we're upregulating them. So I will tell you something, it's not God, I'll probably get into trouble, but it's not published yet. You know, you know how we did six months um on the treatment? Well, it was actually blinded till nine months. So we had three months where both the treatment group and the non-placebo group were on nothing. Okay, so it was a f it was a nine month trial, but six months on treatment, three months on no treatment. The Calico group continued to lose weight. Now it wasn't as fast as it had been, but they did. So what that's showing is, and this is versa placebo, right? So what's that showing is that you have upregulated, so you you've improved that gut brain access. And that's what people are so worried about is what happens when I come off. I've done all of this hard work, and it is hard work, I've done it all, and I don't Want to put the weight back on. So you're not going to uh with Calicurb and we're going to help you uh reset or reboot that cup brain access.
SPEAKER_01Right, right. So what about any side effects? You know, we talked about this before, but are there any digestive side effects or anything that you can expect if you were to take the callocarb three days a week or three times a week?
SPEAKER_00Yeah, um calicurb um has a very, very good safety profile because we only concentrate on the gastrointestinal tract. Um and as I said, less what 1.2% of the hops extract is absorbed in the blood, and of that 0.1% is metabolized in the liver. So really good, you know, really good to take an interaction with any other drugs. And um side effects, uh up to 10% of people uh will experience a laxative effect in the first few days, which is why we have an onboarding, which is just like you titrate up with your GLP1s, we're doing exactly the same thing, but we're doing it in five days. One a day, one capsule a day, the little tiny capsules, one a day or two days, two a day for two days, and then you get up to the full dose, which is two, two, two small catch before lunch, two before dinner. So you can titrate up over literally six days. Um on a very small proportion of people, um, you know, which we call super tasters, uh, um, they may be all right just on one catchful. So if you're the lucky one, you may just stay on one. And that's the reason to titrate up, is to find your dosage and what works for you. So you don't have to take two if you don't need it, um, but we find 95% of people uh do. Uh when I say a super taster, because it's interesting we have different densities of these bitter taste receptors down through our gut. And around 5% of people have the bitter taste receptors from 1 to 25, so and 95 have between 1 to 19. So 5% I always say, hey, you're lucky you would have survived through evolution because you've got a better taste sensation than the rest of us. So, and then other people just nothing. But yeah, we always we've excuse me, we're very clear about that. Umboard, always take it um on an empty stomach or an emptier stomach and with a large glass of water.
SPEAKER_01So, my question about that is I was thinking, what if people wanted to take it with their GLP one? Because your stomach doesn't really empty much on a GLP 1.
SPEAKER_00Uh Absolutely. So you know that's a good point, but it will go through. I mean, it's just literally if it's on an empty stomach, it will go through. And a lot of people, a lot of practitioners are using it in combination, uh, because what they can actually do is they can decrease the dosage, uh, they can decrease the cost um and decrease the side effects, and they're stimulating your natural or your endogenous. And what we get from a lot of practitioners at that day five, uh, day six, that breakthrough hunger that people get, it just manages that. So lower dose, lower side effects, lower cost, and you are also stimulating your own natural. So yeah, I think it's a great, particularly if you're trying to lower your dose, uh, you um you you don't want to get that breakthrough hunger in day six.
SPEAKER_01Yeah, yeah. I think that I mean the dosing, like the cost goes up with the dose going up, and there's a lot of interest for people who want to stay like on a lower dose, and this could give them that ability. They could even maybe spread it out a little a little more.
SPEAKER_00I I always you just got to be careful. I always say, you know, take it on the uh on the injectables on that weekly dosage because it's it's the it's how you it's how it degrades in your body and you want it to to keep at that level. Um so I always say that, but in use Calicurb as well, but hey Kelly, if you're getting that breakthrough hunger. Uh and um, yeah, and then you really set up a lot better for when you come off.
SPEAKER_01Yeah, I and and always like whenever we talk about dosage, I'm a dietitian, not a doctor. So always talk with your doctor about your dosage.
SPEAKER_00Yeah.
SPEAKER_01But um, in terms of the future of Cal Curb, you guys have done four clinical studies? Six?
SPEAKER_00Yeah, four. So, well, if you count all of the in vitro work, I mean there's a lot more. Um, but yeah, we've um we've done four human clinicals so far, and we'll continue to do them. So we've got some really exciting work. So we're a science-led company. You can see that in everything. We put a lot of money into our research. Uh, in fact, it's our first value, which is science-led. Uh, and the second one is customer success because you know it's got to work uh and it's got to be science-led. Yes. So we've got some really great um work coming up. Uh, we'd love when we're wanting to do uh another clinic in postmenopausal woman. Uh, and you're gonna say, why not? Perimenopausal, it's very difficult because you've got hormones going all over the place in perimenopausal stow and postmenopausal will do it. Uh, and also because that's just the time you we know our metabolism slows, all of those things happen, and I think that's when you need some of the really the helper. Um, and remember, it's essentially starting to get more of that visceral fat, you know, that peribally. Um, and we've just seen from the clinical, you know, we lost, what, three and a half times more visceral fat uh than the placebo alone, uh, and we're looking to do one in adolescence. So um, as I said to you, adolescents are, you know, you know, um one in four adolescents are overweight. Uh, and this is just is this a great natural tool to use um to help them during those difficult 10 years, um, just to help regulate that that diet.
SPEAKER_01You guys remember my conversation with Beth a while back, the one that became one of the most popular episodes? Well, Beth is from Tide Wellness, and that conversation is the reason I'm comfortable telling you about them today. So many people lose weight on Jill P1, feel amazing, and then six months later, they're back to where they started because the program ended or the provider disappeared, or they were never set up for the long haul. But Tide Wellness is built differently. Licensed providers who actually adjust your dosing as your body changes, a real care team you can message when you hit a plateau or have a question or need help. Nutrition guidance designed specifically for how GLP1s change your appetite. And if you've got questions, you can book a consultation and actually talk to a provider, a rare find in this space. If you're looking for more than GLP1s, they also do microdose GLP1 programs, hormone therapy, longevity peptides, and the kind of support that matters when you're trying to feel your best long term. Tide is built with support by a team that really cares. Go to tidewellness.com backslash GLP1 hub and use the code GLP1Hub50 for $50 off your first month. Again, it's TideT Y D E wellness.com backslash GLP, the number one hub, and the code is GLP onehub50. Yeah, yeah. Um, I'd be interested in that too, because adolescence still is a period of growth, so you wouldn't want to suppress too much, you know, but then you're right in that there is a also an obesity problem in the adolescent, basically.
SPEAKER_00Yes, you don't want to suppress, no, absolutely, but you want that balance. So it is a lower dose. You know, the theory is that um adolescents or children have a better gut brain access because, you know, they've got their alpha cells, everything's new, um, you know, when we get a bit older, you know, and just everything we've done in life, you know, it's it degrades a bit, which is why I always find it fascinating with young children when they go, No, I'm not hungry, and we try and force them to eat. You know, that's their body telling them they're not hungry. And I think we've got to listen to um that that inner brain of a child talking sometimes.
SPEAKER_01But how do I know I'm not sometimes they're in the pantry right after dinner when they weren't hungry for dinner?
SPEAKER_00That's true as well.
SPEAKER_01As a mother, as a mother of of young children. So in terms of Calicurb um came on my radar about a year ago. So, how has the the reception been of this of this medication? Maybe like cool anecdotal studies or feedback you've gotten from your customers?
SPEAKER_00Uh, look, we uh it's been amazing. Um we sold a quarter of a million packets last year or bottles last year. Uh we get a lot of feedback, we encourage feedback. Um, and you know, the most common is uh you take the noise out of my brain. And, you know, I've stopped the craving, you've taken out. Um and yeah, that's it, that's probably, you know, yes, the weight will follow up, but the key thing is you take that noise out of my brain. So um, yeah, great stories, great people. Uh and yeah, it's just another alternative. As we always say, Anna, it is a tool in a toolkit. You know, you want to use it with great dietary advice or with that. Because if you go from ten donuts to eight donuts, you're really not going to make a big amount of difference. So think of us as a tool. We're not a magic pill. Think of us as a tool in a toolkit. I love the fact that you don't have to titrate up any further. You get to your dosage, it is um, it lasts for four to six hours, you um and it's degraded in 20 hours. You can come in and out of it. And that's how, you know, that's how people they'll get to their goal weight and go, yeah, well, I'm just going to keep some and if if I feel my pants are getting a bit tighter again, or I know this is going to happen. Uh the other thing I would say, one good um anecdotal is one thing we got back that we'd never actually thought about. Um, one person using it is I have to be more thoughtful about my meals. So because you're taking it, you know, an hour to an hour and a half, say before lunch, you've then got to think, well, you know, I'm gonna take it, but I have to be more thoughtful about my lunch. So I won't be just snacking all the time. And it's sort of unintended consequences. We never thought of that. But if you think about it, it's like, yeah, you do. I'm taking it say at 10 or 10 30, but then I'm going to eat my lunch. So I want to be thoughtful about what I'm eating.
SPEAKER_01Yeah, yeah. I think even I mean, even just like the clinical study, maybe that was some of the placebo people, the little bit of weight they lost was just they were being more thoughtful, right? So you gotta take this thing, and then you're like, okay, well, I'm not gonna go eat a hamburger now that I'm take I paid for this calicurb and I'm gonna use it and I want to get the max out of it, of course.
SPEAKER_00Absolutely. But the interesting thing is you'd always see this in placebo. It goes down a little bit at the start and then it bounced back up again. Um, and then I'll send you the study, it's amazing. But the the first three months you just get this wonderful um drop down. Uh so yeah, it was um yeah, very exciting.
SPEAKER_01So well, where can people learn more about Calocurb um and and find product?
SPEAKER_00So, and if you go to our website, um it's Calicurb, which is C A L O C U R B dot com. And it's got all the science on it. Uh, it's got videos, it's got literally, it will take you through that 16 years of um that clinical research and where you can get it. So you can get it online, um, you can get it at Amazon. Um, but the other big thing is um we do sell to practitioners um uh through the US. So, you know, we often say go and talk to your practitioner about it as well.
SPEAKER_01Yeah, that's awesome. Great. Well, definitely everybody should should check it out as a good, you know, alternative and and way to continue to manage this weight thing because we know that it's an ongoing journey.
SPEAKER_00Well, you're surrounded by wonderful food. You know, we all are, you just want to, you know, just think about what we said, modernize human consumption. You've got that hindbrain, absolutely fabulous, but it never evolved uh uh as the world around us evolved, which you know drives you to eat. It was amazing. You know, it got you out of your caves, it got you going. But now, you know, you know, we just go, we roll up to somewhere and buy something.
SPEAKER_01Yeah, it's it's just too easy. Thank you so much, Sarah, for being here. I really, really appreciate it, and I hope that you will come back to share future studies.
SPEAKER_00I will, Anna. Thank you so much. It's been great talking to you.
SPEAKER_01Thank you. Thank you so much for listening to this episode of the GLP One Hub Podcast, and thank you again to Calocurb for having Sarah Kennedy come back and talk about their new study results and for sponsoring this episode. If you're enjoying the podcast, I would love a five-star review. Apple Podcasts is great. You write a little message about it. Spotify would be amazing. You don't even have to write anything, just click the five stars, and that would be really, really helpful. It is a free way for you to say thank you for all the hard work that we're doing over here at Joe P1 Hub. And I look forward to seeing you in the next episode.