The Loop Podcast: Peptides, Longevity & Women’s Wellness

EP 52: Peptides Aren’t One-Size-Fits-All… Here’s What Actually Works | Telehealth Mistakes + Custom Protocols | Anthony Castore

Stephanie Gambetta Season 1 Episode 52

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0:00 | 1:14:42

Peptides aren’t one-size-fits-all—and that’s exactly why most people aren’t getting results.

In this episode of the Loop Podcast, Steph sits down with returning guest Anthony Castore for Part 2, diving deep into the real strategy behind peptide protocols, telehealth pitfalls, and why personalized coaching matters more than ever.

If you’ve ever felt like peptides “aren’t working” or you’ve been handed a generic plan with no real support, this conversation breaks down exactly why.

Steph and Anthony unpack:

  • Why cookie-cutter peptide protocols fail
  • The biggest mistakes happening in telehealth right now
  • How to actually build a personalized peptide plan
  • Why “less is more” when it comes to training and recovery
  • The truth about GLPs—and why they don’t work for everyone
  • How mitochondria health impacts everything from energy to fat loss

They also walk through a real case study of a perimenopausal woman struggling with fatigue, hormones, and plateaus—and how dialing in her protocol, lifestyle, and training changed everything.

This episode is part education, part reality check, and part roadmap for anyone serious about optimizing their health the right way.

Because at the end of the day—it’s not about doing more… it’s about doing what actually works for your body.


Peptides discussed in this episode:

SS-31 (mitochondrial support research)

MOTS-c (metabolic + longevity research)

Tesamorelin (fat metabolism + GH signaling research)

Ipamorelin (recovery + GH pulse support research)

CJC-1295 (growth hormone support research)

Thymosin Alpha-1 (immune support research)

5-amino-1MQ (metabolic support research)