The Metabolic Edit

Leaky Gut Explained: The Hidden Root Cause of Fatigue, Hormones & Autoimmunity : ep.15

Megan Rupp

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If you’ve heard the term “leaky gut” and wondered if it’s just another wellness buzzword — this episode will change your mind.

Leaky gut (a.k.a. increased intestinal permeability) is real, measurable, and one of the most overlooked root causes of everything from bloating and food sensitivities to migraines, fatigue, autoimmunity, and hormone chaos.

In this episode of The Metabolic Edit, I break down the science of gut permeability, how it shows up in the body, and what you can actually do to test and repair it.

We cover:

  • Leaky gut symptoms beyond digestion — skin issues, brain fog, migraines, joint pain, even mood swings
  • Root causes: stress, processed foods, antibiotics, NSAIDs, infections, toxins, and more
  • Functional testing (why I use zonulin + full GI-MAP) to get the full picture
  • Healing strategies: whole foods, collagen and bone broth, intermittent fasting, key nutrients, sleep, stress management, and microbiome repair

Leaky gut isn’t just about your stomach — it’s about your entire system. Once the “coffee filter” of your gut lining is compromised, your immune system, hormones, and energy all take the hit. The good news? Your gut can heal when given the right tools.

This episode gives you the clarity (and strategies) you need to repair your gut lining, calm inflammation, and reclaim your energy for the long haul.

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