Fuel with Erin

Peptides for Women: A Foundations-First Guide with Jennifer Woodward

Erin Martin Episode 31

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Peptides are having a moment — GLP-1s, BPC-157, growth hormone secretagogues (GHSs) — but most of what you're hearing skips the part that actually matters: none of it works if your foundations aren't in place. 

Jennifer Woodward, a Certified Functional Diagnostic Nutrition Practitioner and Board Certified Functional Wellness Coach, and host of Peptides for Women, joins Erin to break down what peptides actually are, which ones have helped her and the women she works with, and why she requires protein, minerals, strength training, and sleep basics before adding peptides. She also shares which ones are worth your money in midlife — from GLP-1s for metabolic reset to the KLOW Stack for joint and gut repair. 

We also get into the research behind peptides, how to avoid sketchy sourcing, and client stories that show peptides can mean very different things depending on where you're starting from. This one is your foundations-first, no-hype guide to peptides.

Resources from this episode can be found at: https://www.fuelwitherin.com/podcast/v/shs22se79tdcxgk9ty6klklahyaewy 


CONNECT WITH JENNIFER

Instagram profile | @jenniferwoodwardnutrition 

Website| https://jenniferwoodwardnutrition.com 

Podcast | Peptides for Women


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Disclaimer: The information provided in this podcast and its show notes is for informational and educational purposes only. It is not intended as medical advice or as a substitute for the advice of a physician or other healthcare professional. Using this information does not create a doctor-patient relationship.


Do not use this information to diagnose or treat any health problem or to prescribe any medication or treatment. Always consult with a qualified healthcare professional before making changes to your diet, exercise routine, or medications, or before starting any herbal or nutritional supplements. Statements regarding dietary supplements have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease. The use of any information provided is solely at your own risk. This disclaimer also applies to any of the guests on the podcast.

SPEAKER_00

I tell people that your body has been running on peptides since the day you were born. They're these signaling molecules that basically restore communication within your body. And so it really is this miraculous way to restore communication into bodies that have been so broken by the environment and stress to communicate with itself better and function better.

SPEAKER_01

Hello and welcome back to Fuel with Erin. And in this episode, we're diving into the world of peptides. I first heard about peptides when I had the CEO of Joy Wellness, Katie Whalen, on, where she talked about peptides being the icing on the cake when you have all the other foundations down. And since then, there's been a lot of noise around peptides, what they are, what's safe, what's not. And so in this episode, I sit down with Jennifer Woodward, who's a certified functional nutrition practitioner and board certified functional wellness coach, specializing in women's hormones and peptides. She's also the host of Peptides for Women podcast and has worked with thousands of women to help them navigate changes in midlife. So today I get her perspective on what she's seen work for women. So for herself and for her clients. And for me, this conversation really just scratched the surface and is not the complete whole story. As you guys know, I am not a doctor, so I'm binging on peptide information right now. And I want to synthesize and share what I've learned so that you guys can make your own informed decisions. So you have agency, you can work with a physician and understand your body and what's best for you. And if there's one thing I've learned about health and wellness in my 20 years, it's that we all want the easy button, myself included. Sometimes we just don't want to do the unsexy basics because it's just not human nature. We seek the most efficient way to do things. And I think that's where peptides are becoming controversial. There's a lot of peptides out there that are all very different and do different things. The most popular FDA-approved peptides right now are insulin and GLP1s, like Ozempic and Wigovee. And then there are a ton of peptides, many of them that you're going to hear today, that are not FDA approved. And so, for example, microdosing GLP1s is an unofficial term that's generally describing taking a fraction of the standard dose. And it's not an FDA-approved dosing strategy and lacks formal clinical validation. And then on top of that, there's gray market peptides that don't hold FDA approval as finished drugs. There's the black market. So the various peptides, where and how you get them, all those details matter. And long story short, right now peptides are super trendy. And I do believe that people need to better understand the whole story. So after this podcast with Jennifer, I did a ton more research and we'll be recapping and sharing those learnings in the next follow-up episode. So I highly recommend you listen to that deeper dive. I have links to all the sources I was combing through so you can hear and read for yourself. Because again, I do want you to have all the pieces to the puzzle, in addition to what's emerging as some of the potential cool things that peptide therapy is doing. And so with that 80-point precursor, I'm excited to get into the conversation with Jennifer to hear her take on what she's seen as a nutrition practitioner and functional wellness coach as your fuel for today.

SPEAKER_00

Okay. So I tell people that your body has been running on peptides since the day you were born. They're these signaling molecules that basically restore communication within your body, right? So we have peptides like BPC 157 that tells your body to bring down inflammation. We have peptides like a GLP1 that tells your body, hey, I'm full. I don't need any more food. Or, you know, let's not quite digest that just yet, or let's bring down blood sugar. And so it really is, you know, it's almost like this sort of, if I say miraculous, I don't think it's too big of a word like this, almost like miraculous way to restore communication into bodies that have been so broken by the environment and stress and microplastics and, you know, all this junk, right? Of just living here on earth to communicate with itself better and function better. But they're endogenous. You make them yourself. So they're not scary to the body because the body already makes them and recognizes them and they work. They're not drugs, they're not supplements, they're this whole other class of tool that is just really pretty flipping incredible.

SPEAKER_01

Yes. And so technically, did I get it right in that they were they are a chain of amino acids, and I was trying to find how many are actually naturally producing in the body. And the only number that I could find was over 7,000, which means like maybe that's the amount that we potentially know of, but there's so many.

SPEAKER_00

There's so many. And we're using AI actually to, you know, synth to locate and synthesize even more of these peptides, but we're just scratching the surface. And you're right. So peptides are like really, really small chains of amino acids, like small, you know, two to 50 molecules. And then proteins are like these larger structures that are like more, you know, like uh, like, like 3D essentially. Um, and then we have like hormones that are even bigger molecules, but but they really are this little tiny, like the little engine that could, you know, little tiny, very targeted um text messages too, targeted communication. So like one peptide sends one specific signal. And if the body doesn't need that signal, the peptide just cruises right on by, right? It's not gonna do anything that your body doesn't need or doesn't want it to do. And the signal that it sends is so precise that the body doesn't recognize it as a different signal. You know, I'm a former pharmaceutical sales rep, so I used to sell some really big drugs, right? Like drugs that would like carpet bomb your microbiome, right? Or like bring down your cholesterol, even if you needed, you know, somewhat protective cholesterol, high cholesterol for your brain. Peptides are different in the fact that they are they're so precise, they're so specific.

SPEAKER_01

Yeah, and I think that's the piece where I get overwhelmed is that there's so many varieties. It sounds like there's an amazing amount of things that you could help optimize your body. So I'm curious, kind of two-part question for you. What have you personally played with? And then I also know that you work with thousands of women in midlife. And so, what tends to be one that you often will recommend or see women take advantage of the most with so many being out there?

SPEAKER_00

So fun. I always tell people I'll try anything once. So I started my peptide journey and then it's been really hard to stop. But I'm like, oh, I could try that one and that one. And so um, basically 18 months ago, I started with the GLP one. I didn't want to. I'm a health coach. I thought it was cheating. I thought I was, you know, disappointing all the people I'd worked with. But man, when I saw that GLP one reduced my inflammation and helped me lose 15 pounds that I gained, even though like my workouts were the same, my protein was the same, my diet was the same, like everything was the same. I was just in midlife now and I just felt really like a fraud. I was like, dang it, like I'm telling all these people, you know, how to eat and how to move. And here I am 15 pounds heavier than I want to be, and I just feel crappy about myself. And so my own coach at the time introduced me to the concept of a microdose of a GLP one. And again, at first I was like, oh, hell no, no way. And then I was like three weeks in, like, okay, maybe I could consider trying that. Then I tried it and I was like, holy crap, my food noise is like immediately gone. My inflammation, I can tell, is down immediately. I started losing weight immediately. I just, I just felt better, like I felt like my body started to communicate to itself again. And once I realized how, you know, helpful and powerful and effective, but still like gentle and safe the GLP one was. And I'm not a doctor, so this isn't like medical advice. This is just my own, you know, opinion, what's happened and worked for me. I was like, okay, yeah, what else is there? And so I started layering in BPC 157, TB500 for inflammation. I had a lot of inflammation at the time, uh, plantar fasciitis, psoriasis, just like felt inflamed, you know, have a high viral load, you know, all these things that all of us health coaches have been dealing with forever, which is why we got in the health coaching space to begin with. Like, fix myself. So a lot of inflammation. Started seeing that come down, added more of these anti-inflammatory peptides. I started working with glutathione, which is, you know, like I've used it as a supplement in the past, but as a peptide, it's so much more effective, you know, for liver health and inflammation, just detox. Um, I started working with the growth hormone secretagog. So started with semerelin and then moved on to tesimerelin. Those really help with muscle recovery, belly fat, sleep, libido, like everything a midlife woman wants. I was like, yeah, sign me up. Let's let's do that. Um, I have worked with KPV as well, which is an anti-inflammatory and gut health peptide. I've done a couple of the bioregulators like epithalon, um, one for my pineal gland and kind of HPA uh, you know, regulation. I've done oxytocin. I've done PT141, which is a libido peptide, um, which is compounded with tadolophil. Um, and then oxytocin, that's all over like three libido peptides. Uh, let's see. I'm sure there are some I'm forgetting. I'm just picturing my little like temporal.

SPEAKER_01

You've tested a ton then.

SPEAKER_00

Yes. And then I know the second part to your question was what do my women use the most? GLP1s, hands down. I will tell people like, I know you want to experiment with all these other peptides. You want libido, you want to lose your belly fat, you want to reduce inflammation. I'll save you a thousand dollars. Start with the GLP one, it's gonna do all of those things for you and you're gonna feel the best. Then after you've been on that for three, six months, you're feeling better. Then go ahead and explore some of the other peptides.

SPEAKER_01

And that one specifically, there's so much news and noise around GLP1s right now. So break down how that one works. And then I'm also curious about what other foundations you like to see in place before people start dabbling in it.

SPEAKER_00

Great question. Yes. Okay. So GLP1 stands for glucagon-like peptide one. Again, your body already produces it. We produce a little bit in the gut, we produce a little bit in the brain. And a GLP one has two actions. Number one, to send the correct signals to your brain that you are full. So a lot of women, they don't know when they're full anymore. They've dieted so much, they've exercised so much, they've deprived themselves so much that they're like, I don't, I don't eat breakfast, you know, I'm not really hungry for lunch. And then I eat like, you know, I binge at night wine and chips and salsa just because like I've deprived myself during the day. We we just aren't in tune with our cues anymore. So a GLP one can help restore correct satiety clues to the body. It also does delay gastric emptying. So it will slow down the absorption and digestion of food in, you know, your stomach and your digestive tract. And some people are like, well, that's a bad thing. And it can be a bad thing if you have previous, you know, intense gut motility issues, but it's also doing, you know, something helpful for the body. You stay fuller longer, right? You're more satisfied with really what I think is a human normal amount of food. Like anyone who's in the West, right? We we just have this weird relationship with food. We eat too much, we eat too little. You know, we've got these statistics that, you know, Americans eat up to 3,500 calories a day. We have women on Instagram who are eating 800 calories a day. Like it just, it's really fucked up what we've done to our bodies. And so this just kind of, you know, I I've had this experience. My women have had this experience, my men have had this experience. Uh, a proper dose of a GLP one, which we like to be as low as possible, makes you hungry for normal food in normal amounts at the right times. Like it's really simple. You just return to basics. Like you want to eat healthy, you want to eat enough, but not too much, and you eat normal meals. It's pretty great.

SPEAKER_01

Yeah. So when you started it, like what was did you inject it? I think there's, I've read there's oral, there's like so many different ways that you can take it. What how did you take it? And what uh way do you see usually working best for women?

SPEAKER_00

I injected it. I wasn't really, I mean, I was a slightly scared of needles. I think that most people are, and that's a relatively healthy fear. But I I know that, you know, if you're injecting something, the absorption rate is so much more, uh so much higher than it is with any other form, right? So transdermal, you really don't um absorb that much. Oral, really low absorption rate. And so, you know, I've seen in my practice that the pills like GLP1 pills and GLP1 drops, they don't really do much. It's it really is kind of a waste of money. If you're scared of needles, like you could try it for a little bit of time, but then don't come back and be like, you know, oh, it didn't work. It didn't work because you're not absorbing that much of it. But if you can, you know, kind of practice getting over your needle fear. And I'll tell you, these are insulin needles. So they're 30 gauge needles. You can find them on Amazon. It's a very thin, small needle. And GLP1 is a big enough molecule to where um it doesn't really it doesn't hurt necessarily going in. There's some larger molecules like GHKCU or glutathione. We call those like spicy peptides because they can roll, they can hurt. They can hurt with it. Like it burns a little bit when those bigger molecules go in. Um, but GLP one's pretty innocuous when you inject it. There, it's rare that you actually have like um pain or even feel it. You might feel like that little almost like mosquito bite as the needle goes in. But you're also like you're injecting it in your belly fat. Like right, you pinch your fat, you know, and then you like inject it. And so it's almost like you're you're it doesn't hurt that bad either because you know, you've taken precautions against the pain.

SPEAKER_01

And I know one thing that you've I've heard you talk about a ton is having those foundations down. So I was wondering if you could elaborate on that and what you look for when you're working with women of what foundations to have in place before exploring something like GLP1s. Because I think I've heard other people also talk about like, okay, like peptides being the icing on the cake. Like you can't peptide your way out of something that's just foundationally incorrect. And you can't have benefits of peptides if you have all these other things going on. So I'm curious for you, what was your foundations that you wanted to make sure you had in place? And what do you recommend for women and what do you look at for women before you recommend or look at peptides?

SPEAKER_00

Yeah, great question. And it's a lot of the stuff that your audience already knows, you know, like the things that you're like preaching every day, like just general well, like ways to take care of your wellness. And I will tell my clients, yes, you can absolutely inject a peptide if you're uh, you know, quote, metabolic dumpster fire to borrow a term from Jay Campbell, but it's not gonna work as well. And then you're gonna be upset because you kind of wasted your money, you're not gonna feel that good. And you're not gonna feel that good, not because a peptide didn't work, but because you're not taking care of yourself to begin with. A peptide can't fix you not taking care of yourself. And I think women are really at a disadvantage, you know, especially in our 30s, 40s, and 50s when we're trying to take care of our kids and our husbands and our families and our careers and, you know, maybe our aging parents. We're just kind of burning the candle at both ends. And I hear time after time after time from my women, I don't have time to take care of myself. And so I do understand that it's really hard to, you know, almost have this, you know, part-time job of taking care of yourself. But I would encourage people, you know, maybe start with one new thing, two new things before you add the peptides, just so your peptides work better. And those foundations in my practice that I do for myself, like day in and day out, they've just become habit for me. And I try to make them habit for my clients as well. We do 100 grams of animal protein every single day, at least. We do minerals. So I'm literally drinking my minerals right now, like high potassium minerals and enough sodium just to keep your electrolyte balance high. Um, strength training at least three times a week. And that that looks a little different for everyone, but like you don't have to go train for a half marathon anymore. You're 45, you know, like chill the fuck out. Like you don't have to go to CrossFit or Orange Theory. Like, let's save that for the 20-year-olds. They they can do it at this point in our life. You know, a little bit of zone two cardio, right? Some fat burning cardio, not an hour a day, maybe like, you know, 15 minutes a day, three times a week, and then, you know, 45 minutes of strength training. Invest in some, you know, personal training just so you know that you're lifting correctly. You don't have to have a personal trainer forever, but if you spend a month or two with someone so you have good form and you know what it is to like, you know, craft a quality workout routine that's gonna pay dividends for you for bone health and muscle retention, posture, even things like libido, you know, obviously belly fat too. So exercise from that component. I used to like espouse walking 10,000 steps a day. I don't think that most women have to do that, honestly. I think it can be helpful if you have the time. I also think it can make you really, really tired, you know, and inflamed. And then you're not, you know, getting to your gym workout because you've been walking 10,000 steps a day and you're frustrated because you're not losing weight on 10,000 steps a day. I would just be like, let's focus, let's, let's focus a little bit more, maybe on meal prep and strength training, right? Instead of an hour and a half a day of walking. That's just me. Um, and then, you know, making sure you get fiber. I tell my women, I know that, you know, I can scare the crap out of you and you think you should never eat fruit. But I have my women eat one piece of fruit with every meal every day, three, at least three pieces of fruit a day for potassium, magnesium, for fiber, for water, easy water, really. Um, and just for, you know, that that sweet craving being reduced. Like I find that the more fruit they eat, the less they want Girl Scout cookies or, you know, sour gummy worms or whatever, just because we're supposed to have a little bit of it.

SPEAKER_01

The things that we're scared of because whatever we grew up with, that now we have a rule in our head that this is a no and this is a yes, or this is clean eating and this is not.

unknown

Yeah.

SPEAKER_00

It definitely is. Were you do you feel like you had that in your background too? Like you were a little scared of fruit for a while?

SPEAKER_01

Not fruit. Um, because I would just naturally go towards whole foods, but I wouldn't incorporate as much whole grains and carbs as I needed because there's so much processed foods that I would just avoid processed foods and then think processed foods equated to carbs. So that was it for me in the past, where I just naturally avoided carbs because I didn't have the knowledge or incorporate the right type of good carbs, you know, like sweet potatoes now are in my diet where they weren't before, oats. Um, I'm trying to think what else I've thrown in there. Brown rice, quinoa, faro, a bunch of that where that just wasn't a natural go-to, as like carbs. It was, I always thought pasta or something processed. So that's been a shift, which, yeah, you absolutely need carbs.

SPEAKER_00

Yeah. Especially if you want guns like Erin's.

SPEAKER_01

Because I'm lifting weights.

SPEAKER_00

Yes. But you have the you have like the energy to lift weights because like you're eating carbs. I just think it's a yeah, like a self-perpetuating cycle for so many women. They're like, Can I take a peptide to give me energy? I'm like, no, but you can eat more calories to give you energy and eat carbs to give you energy, and then you can, you know, exercise to give you energy, and then you'll sleep better, which will give you energy. So it's really hard. I mean, I think people like anything else, like anything else, look at peptides as like a cure all, a fix-all, or like reductionistic. But it really is so important to get those foundations in. And like, like we were just talking about, Aaron, they're not, it's not like they're super complicated. Like eat food, move your body, you know, kind of live your life with the rhythms of the sun, because you're a woman and you need to live in rhythms, you know, and not like a man. Um, and just like care for yourself the way you care for, you know, a baby or a puppy, and then add the peptides in and see everything start to rock and roll.

SPEAKER_01

And that's why I asked so much about the foundations too, because when it comes to GLP wands, I would be curious to hear the variety of women who do come to you. And I could imagine that there's some people where yes, like there's a great fit, you know, however much, you know, you need to lose or that you want to lose or get less inflamed and feel better. And you've done all the foundations and tried all these things. And I can imagine that there's another group where they haven't done the foundations, or they may be wanting to lose like five pounds, where it's like, okay, like maybe we need to rethink health if like you're just trying to like cruise off the five pounds, but you're not inflamed and you're healthy. So I it just seems like there's probably so many women coming to you for a variety of reasons where you're trying to help figure out, like, okay, like what is your actual true baseline health and when can it apply? So I'm curious what type of stories do you see? Like, how do you navigate that when it's just such a hot topic right now and it seems like everyone's interested in it?

SPEAKER_00

Totally. I thought for, you know, a long time, maybe six months, a long time, you know, in a relative sense, kind of at the beginning of this, that, you know, people were gonna want to add peptides onto their coaching journey with me. And I found very quickly, because I do work with the telehealth compounding pharmacy, that some people they just wanted access to good quality peptides. And so there's a part of my business where like I help people get access to good quality physician oversight peptides. And for those people, I was like, I feel like I can't just like help them get peptides and then leave them to their own devices. As a coach, I just felt like it was incumbent on me to make sure that I was caring for them the best way possible, even if they didn't hire me as a coach. And so I built an app for those people where they can track their injection. It's got a meal plan, it's got exercise, it's got supplement, it's got lifestyle. It but like everything I would do for my private clients, I've kind of Given to my peptide clients just so I can be like, I feel like I've done my due diligence to make sure that those foundations could be met. Were they willing to put in, you know, the effort? And for the most part, most of them are. They do, right? Then for my coaching clients, it's a little bit different because I've been in this space for so long. You know, I've been helping women lose weight and feel great, you know, since uh for the last 11 years. And so that part really hasn't changed because the foundations piece is the most important piece. So it's funny, I'm thinking of this one particular client, Erin. Her name's Anna. She's fantastic. She was with me as a private client, and we actually, you know, we're working together with my programs. Like the foundations that we do, functional lab testing, like, you know, coaching. And she lost, she lost 69 pounds. Like, and she did have quite a bit to lose, but she just killed it. Like she did everything I asked her to do. She killed it. And then she actually lives in my town, and we decided we were gonna meet in real life and we're gonna play pickleball together one morning. So we're out there at pickleball, and it's a Friday morning, and like I casually mentioned, you know, oh, my, you know, my peptide episode is going live a little bit later today. I was just finishing something up for it at pickleball. And she's like, What do you mean, peptide episode? So Anna listened to every single peptides for a woman podcast, came to our next meeting like less than a week later after binging the whole thing. She's like, I'm so mad at you. I can't believe you've never mentioned peptides to me. You clearly think they're amazing, and you've been letting me do this whole thing without peptides. I was like, Anna, I'm so sorry. First of all, like I wanted you to know that there are so many amazing things that your body can do if you put in the effort and look, you've lost 69 pounds, like you've done that all on your own. It wasn't the peptide, it was you. But now you're to a point where you're sleeping well, you've got good muscle mass, you've dialed in your diet, like things are rocking and rolling. And so now is actually a great time to add peptides. So we did add a GLP one and she lost another 17 pounds after being on, you know, a plateau for two or three weeks. And so that's one of my favorite peptide stories, just because it's not something I generally start with for clients who are hiring me as a coach, but it's something that can be a great adjunct if, you know, your body is primed and ready, you know, for for peptide therapy. And I'd say Anna is probably um, probably, you know, quite similar to a lot of of my clients. Um, I am getting a newer wave of clients of women who don't really have weight to lose and they just wanna, they just want to feel good. They're just kind of broken down, they're burnt out. And so the same, you know, foundations apply. And then we'll add things like growth hormones or GHKCU or the cloth stack or glutathione. Um, and so I'm really loving the results that those clients are getting with just feeling good, sleeping deeper, having more muscle, bringing their libido back, hair, skin, and nails, um, and not necessarily just focusing so much like on the weight loss side. But um, every, every new client is just like exciting to me. It's like a new puzzle.

SPEAKER_01

Like, oh, what are we gonna do? Yes. Which also the funny thing too is if you can improve sleep, include improve energy, you know, improve all these other facets that can also help with fat loss because we know how important sleep is and all these other foundational factors. So it can get there in many different ways. And so for a new person like me, where is a good place to start? Is it with labs or a Dutch test to better understand your body and understand what needs optimizing? Because I think that's the other piece is like, how do you even go about it? When you listed all the different things that you've tried, I was like, oh my gosh, how does someone even know like where to go or what to do or how to start? So does it start with labs or is there something else?

SPEAKER_00

Generally, peptide therapy does not start with labs. At least, like at a so I work with a 503A compounding pharmacy. We don't require labs to necessarily have a prescription for peptides. There are some extenuating circumstances, like you can't be pregnant or have an eating disorder, have active cancer, like you have to fit within the BMI, you know, boundaries. But there is not any like perfunctory lab work that has to be done before you start peptide therapy. Now, what I've learned over the last almost two years is that running lab tests can be awesome just for you. Like if you're trying to biohack or you're working with a coach and you're trying to figure out are these peptides actually helping me? And so, yes, like if you are on an actual like wellness journey, a fitness journey, then you can order some of your own labs with like labs direct online, or like I use rhythm health, which is an at-home lab testing. The kit comes like once a month for 80 bucks. So that's a great, a great option for you to test like hemoglobin A1C and blood glucose and C reactive protein and you know, some of these metabolic and inflammatory markers that you'll start to see come down over time, normalize over time. If you're on something like a GLP1 or BPC 157, um, you know, you can test for like ALT and AST and GGT if you're on glutathione to see if your liver and your gallbladder are working better. And actually, like I wrote all that down. My book's coming out in a couple months, The Peptide Promise. So I have a whole lab testing section there with like optimal ranges, just so people can either self-test or bring it to their physician and say, like, I do I do want to test. Like, is there a way for you to help me? Um, but just to start with peptides, it's not, it's not a medication necessarily. So it's not um, you don't have to have labs. It's just like a nice to have.

SPEAKER_01

And so are you basically going off of symptoms then? Because it would blow my mind if you're if you can't nail the root cause of what might need to be optimized or what the issue is to then throw something in. So how do you navigate that piece? Is it the symptoms-based or totally okay?

SPEAKER_00

I love this. So if I'm working with someone in a private client capacity, like we are running all the tests. We're running a Dutch test, we're running a hair tissue mineral analysis, we're running a GI map, we're running a food sensitivity functional thyroid panel. So I do have data on my private clients. And then we also have like a complete symptom history. Plus, I know that like I meet every single week with them. So in that way, I'm able to kind of like encourage them, like talk with your doctor about this peptide. This might be a good one for you to start with or a good adjunct. But like the people who are just like, I'm facilitating that, you know, people who are just like wanting peptides, good quality peptides, and are like, here, you know, this is the one I sort of want. And then they purchase it. I don't, I don't necessarily have control over that, but I do see that generally people who are ready to take that step to purchase peptides, especially women, especially midlife women, have done their due diligence to determine whether or not like that is a peptide they could or should use. Plus, a high quality peptide is not cheap, right? Like a GLP1 microdose to GLP1 2.5 milligrams, $239 a month. I spent way more than that on crappy supplements that don't work. But for some people, that is a little bit of sticker shock. And so you're not just like, most people aren't just like buying peptides willy-nilly. You know what I mean? They're like, okay, I've been thinking about this for a while. I have like 15 pounds to lose. I've done a little bit of research on this. I'm, you know, listened to this podcast, read this blog post, talked with my doctor about it. I'm ready to try a GLP one. And so um, you know, most people are pretty well versed in what to what to do and how to start. And then that's also the advice that I will give when I'm, you know, talking about peptides. If you've got this laundry list of symptoms and one of them is weight loss, always start with a GLP one because a lot of times, you know, those other symptoms are gonna kind of fall by the wayside as your body becomes more metabolically optimized. So I guess the answer to that, Erin, is like it's still working out. It's so new, you know, that there really isn't like a great answer for that, but it's evolving, you know?

SPEAKER_01

Yeah. Yeah. Cause do you know of any research on it that's come out or um that is being done?

SPEAKER_00

Tons. Yeah, I we I actually created a course on this. So we have the peptides for practitioners course, and it's fully research based on every single one of these peptides that we are talking about. There's, you know, over 20 peptides mentioned in the course. It's highly scientific, all peer-reviewed journal articles on you know, these peptides, their efficacy, their safety. The thing is, we don't have a ton of human studies on some of the peptides, for instance, BPC 157, KPB. And the reason is that these aren't, they aren't, the molecules aren't owned by pharmaceutical companies. Usually it's pharmaceutical companies that are putting billions of dollars into these clinical trials trials and research. But we've got this molecule that's basically generic that no one owns. And so who's gonna pay for the trials, the human trials to be done on some of these molecules? Now, with the, you know, really excitement over peptides, there are more studies being done. Um, but the best studies we have, the safety and efficacy of these GLP1 compounds, semaglutide, terzeptide, going back a little bit, lyriglutide, those are hands down. The research is like they're safe and they're efficacious. They don't cause cancer, you're gonna lose weight, you're gonna reduce inflammation. And the reason why is that Eli Lilly and Novo Nordisk, they own those proprietary molecules. So they put their research into developing them and studying them and then doing, you know, all their due diligence with the FDA to get these approved as a pharmaceutical. And so we've got tons and tons of research, like the surmount trials, the surpass trials. Um, these show that over the course of, you know, one year to three years, that GLP ones help you lose up to 23% of your weight of your body weight, generally keep muscle mass as high as possible on par with any other weight loss modality, right? Help bring down inflammatory markers. There's even some new emerging research that shows that GLP ones are associated with, they don't cause or um, you know, they don't prevent cancer, but they are associated with less of an incidence of some of the more deadly cancers we have, like colon cancer and breast cancer. There is research right now with like Alzheimer's and Parkinson's and dementia, um, research with cardiovascular disease and GLP one. So tons of emerging research and published research, particularly on GLP ones. And I expect that, you know, we'll have more of that research in the future with some of these other compounds.

SPEAKER_01

Yeah, that's interesting because I always hear about, oh, we don't know, you know, in the future what's how someone's body's gonna react or be, or so it sounds like there is a ton of research, which I'll have to look at and put in the show notes then too. And so specifically with GLP one, and then I do want to ask about all the other types that are out there because there's so many, um, even just the ones that you listed. But with GLP1, then, how does it work in terms of uh going on it and then how long are you on it? How how often do you take it? Do you wean off? What happens when you go off? Like, how does the actual cycle then of going on it and going off work?

SPEAKER_00

Yeah. So the research is for let's talk about terasepatide, because this is my favorite GLP one. So semaglutide is ozempic. It kind of like started the craze for peptides, like weight loss peptides. That was like circa 2008. Teraseptide is a second generation, like mass-produced, you know, like public GLP one. Like I said, we had lyriglutide, which was once daily, and that was, you know, over a decade ago, two decades ago. But now terzepatide is just the a well-studied, very safe peptide compound for women, GLP1. It's got the GLP1 piece, that glucagon-like peptide one, and then it also has a GI piece. So that's a dual action um basically GLP one. So we see greater efficacy for weight loss with terasepatide with a reduction of side effects, which is really, really exciting for women. And we'll talk about maybe retitrutide a little bit too, but this is why I don't like retitrutide. I prefer terasepatide. And so the the studied doses for terzepatide and the research start at 2.5 milligram. So that's generally the dose that some, you know, companies will use as a a microdose. It's not, it's not technically a microdose. There's no like clear term that defines microdose. It's a low dose of a GLP1. So that right there would be, you know, where a lot of people may or may not start. Um, again, not a doctor just saying like this is what people may do if you were using, you know, a physician. Um, maybe start at 2.5 milligrams. And the half-life for that peptide is about five days. So that means it will stay in your body at that concentration, 2.5 milligrams for up to five days. So the the standard of care for a GLP one is an injection once every seven days. So, like I take mine on Fridays, my husband takes his on Fridays, helps us like get through the weekend, you know, don't feel like you want to eat too much or drink too much, you just feel pretty good, right? There is some really cool research being done right now by Dr. Ian Ellis, where who's developed this proprietary um app that doses your um your peptide a little bit more often, or maybe a little less often, because that therapeutic concentration of what's in the body can either get too high, um, you know, and increase side effects, or get too low and reduce the amount of appetite suppression that you could give. So it is a little bit of a game that each person kind of has to play around with their own. That said, that period that takes a little bit of time to do. So if somebody's like, oh, I want to try torsopatide for a month, I was like, hmm, nope. Nope, this isn't like something you try, like, I'm gonna go try pickleball one week. No, this is like something where you try it. You have to give it some time. Again, the the research studies that I, you know, was talking about a while back, those are two-year studies. We see people continuing to lose weight two years into treatment. We see metabolic effects and you know, inflammation, anti-inflammatory effects two weeks or two years into treatment. And so trying it for a month and then saying it doesn't work is like uh probably not the best investment of your time and money. That said, it is like anything else. So the analogy I like to use is like your thyroid medication. Let's say you're on synthroid, right? And you go to your doctor and your T4 is low. So he puts you on synthroid, levothyroxine, and you go back a month later and lo and behold, your T4 is higher. Well, your body didn't start making its own T4, it's now on synthroid. And so, of course, your labs are gonna look better. What happens if that day, when you find out your T4 looks perfect, you go off your synthroid, and then a month later you're back in your doctor's office complaining about how you're tired again, your hair's falling out, and you've gained weight. Well, it's because the medication was doing what it was designed to do in the same way a GLP one is designed to, you know, have a prolonged effect on people for as long as you're taking the medication. So there's some people who need to be on it for a long time. For me personally, I have a history of an eating disorder, um, bulimia and food addiction. And for me, the mental benefits of not thinking about food, like I haven't binged and purged since I've been on my trzepatide. Now, that's a whole nother kettle of fish. It's not just the trzepatide, there's a lot more that goes into that. But just not having that physical pull and urge is really life-changing for me. And so I continue to stay on a, you know, microdose as long as the Lord allows me to, right? Like as long as I can afford it and as long as it's available, I will be on it. For someone who maybe has like 10 pounds to lose and is pretty metabolically stable and doesn't have a ton of food noise. Maybe they're on it for three months and six months and they lose their 10 pounds. And then because they've put in the foundational work during the time that they're on the GLP one, they're eating enough protein, they're getting better sleep. Maybe their body regulates enough to where they don't notice a huge difference if they wean off their peptide. And so just like anything else, you know, in in functional medicine, it's it, it's very like highly client-specific. So it'd be, I'd be remiss if I was like, stay on it for this long and then you can go off, or be, you know, have this dose and then, you know, that dose is gonna work for everyone. Because number one, I'm not a doctor. Number two, everyone's so different. But essentially, like anything else, you stop taking magnesium, you're gonna be a little bit more stressed, right? You stop taking your GLP one, you might put a little bit of weight back on.

SPEAKER_01

There's so much to it. I think that's where when I just continue to do more research around peptides, I get more confused of where to start because it is so individual to someone. It sounds like definitely find a good practitioner and someone who can talk through so many things and get the foundations done right to then figure out how to layer stuff in. So I'm curious after all the things usually facing women in midlife, we've got fat loss is usually up there. We've talked about a ton. We've also got sleep and fatigue. So, what other peptides are some of the ones that you had mentioned before that can help with those type of things or the most popular symptoms that you hear women come to you with?

SPEAKER_00

Yeah, sleep and fatigue are huge. Women are so tired and they are not sleeping. And so, you know, first line for those particular things after foundations are met are generally the growth hormone secretagogs, right? So this basically restores like the intensity and the duration of the pulse that your body would give to create growth hormone anyway, right? It did that when we were like in our teens and 20s. So we all had great hair and skin and like a high libido and you know, great muscle mass, even though we never really worked out. Like that's the action of growth hormone. But as we get older, that pulse kind of like dies in intensity. It doesn't happen, you know, as often. And so the growth hormones of critagogue start to restore that pulse. So it's almost like an anti-aging, you know, peptide. But since it's working on your growth hormone, it does help you have deeper sleep. You start to remember your dreams a little bit more, which is nice. You can tell you're getting into that deeper sleep. Muscle retention, muscle growth is better. You know, a lot of women complain that they're going to the gym, but they're not seeing, you know, any change with regard to their muscles. Um, libido can come back. And that's it's not like it's gonna fix your libido for a woman in midlife. That's a huge problem, but it can definitely start to help. It can reduce belly fat. A lot of women, you know, are really struggling with belly fat in midlife as estrogen drops and progesterone starts to, you know, fluctuate, their bellies, you know, are there where maybe they haven't in the past, and the growth hormones to create a gox can help with that. Um, basically any, and oh, and hair, skin, and nails too, you know. Um, I've I had extensions for two and a half years, and then we were on vacation this summer in like a really hot and humid place, and I just was like, oh, I'm done with these. And I just like ripped them out and I was like, I'm gonna feel so naked and bald without my extensions. But I've been taking copper peptide and I've been taking growth hormones to Cretagog. And I feel like my hair, I mean, it's not gonna be as amazing as it was with extensions, but it's definitely like healthy and strong, you know what I mean? And I was like, that's really cool to see, you know, the peptides working the way that they said they would. One of those is a growth hormone secretagog, all right. So I started with one called Sumorelin or SMRLin. Um, I like that one because it's a little bit, uh a little bit less intense. So it's a good one for women to kind of ease their way into um, you know, growth growth hormones. There are a couple of other that that a lot of men seem to thrive on. So tesamoralin, which is really good for belly fat and ipamoralin, those two are generally combined together, or ipamoralin and CJC 1295. Um, all of them kind of do the same thing at different, you know, strengths and levels in the body, but men tend to do better on like the CJC, the tesamerolin, ipamerelin, women tend to do better starting with the semorin. Um, it's just because sometimes as your muscles get bigger, um, you retain water. And a lot of times, like for me, when I started, I did an epimerolin, testerolin blend. I put on five pounds and I was like, not worth it. Nope. Mm-mm. Not doing this, going back to semarelin. And so, you know, going back to a less intense growth hormone, so creatogog did, you know, take that water weight off. And it was just water weight, but it was messing with my head, you know. Um and I did feel more like inflamed, right? I could tell that my body was, you know, retaining water.

SPEAKER_01

There's a difference between water in the muscle, which makes you gain weight, but is a good thing, and then just actual fluid retention inflammation. So was it the fluid retention inflammation side of it?

SPEAKER_00

I honestly think it was both. I could tell my lifts were stronger in the gym, but I also felt puffy. Like I f you know what I mean, like kind of just saying your abdomen, like your, you know, arms and stuff. Like, yeah.

SPEAKER_01

Yeah, gotcha. So with some more lin, for example, are you still taking it then? Do you is it an injection weekly? Like, is it the same type of cycle that you talked about with a GLP1? Um, or do you cycle it while you'll take it for however many months and then give it a break and just kind of spot use it? How do you use it today?

SPEAKER_00

So growth hormones are generally a two-month cycle on and a one to two month cycle off. Right now I'm doing a blend of tesamorin plus KPV, which is an anti-inflammatory peptide, a gut peptide. So that tends to keep water retention down and just makes you feel less inflamed. That is dosed five times a week. So Monday through Friday at night, I'll take my growth hormone to kind of help with sleep and then recovery. Um, and then I take the weekends off. And every two months, I'll take one full month off.

SPEAKER_01

Gotcha. And you know so much how you have educated yourself on this. Like I know you've you've used it, used yourself as a test to understand all these things too. And then you've done a ton of research. So are you just like finding all the research out there? How do you stay on top of all these different things and stay educated as well?

SPEAKER_00

I just love this stuff and I've learned from you know some of the best. So I really like the work of Jay Campbell, Monica Campbell, Hunter Williams, Taylor Williams. They have taught me a lot. So everything that they put out, I buy and read. I find that, you know, because they were doing this a long time ago, it tends to be less biased than a lot of what's, you know, out there uh in the literature today. I have, you know, certifications, I've taken courses, I've attended seminars, I've read a ton of books. And then, you know, like any, you know, modern researcher, I have a trusepatide Google alert set up. So every day, a couple of times a day, if there's something happening, you know, with regards to trzepatite, it's coming um, you know, to my Google inbox. But I also just, you know, love this talking to people. I I find that, you know, the literature is one thing and books are one thing. But man, people's stories and the way that these are actually um, you know, helping women particularly and men is so much more powerful than anything I could read in a book. And so it's just like a working. Progress like anything else. But Erin, if I tend to get into something, I'm really into it. So that's probably why it's I love it.

SPEAKER_01

So are there any other stories you can share of specific peptides the different women have taken for either the sleep side, fatigue, energy, like any of those that you can share or come to mind for you?

SPEAKER_00

Yes. Yeah, a lot, actually. Okay. So one is my favorite. My client Julia, who is a CEO in the Midwest, has like the most calming Southern accent. She did not want to lose any weight, right? She just wanted to, she just wanted to feel better. Her energy was low. Um, her hair was kind of like falling out. She couldn't sleep very well. She just was not doing well, right? And so she actually came to me as a client through the podcast. I didn't even meet her. And she bought a bunch of peptides before she hired me as a coach. So when she came to me, she's, you know, had started five different peptides. I was like, damn, girl. Okay, let's talk about like what we're gonna do first, order of operations with like lab testing and then foundations before you actually start adding in these peptides. And so we did all the foundations. We ran a Dutch test, we ran a hair tissue mineral analysis. We had to move her from eating one meal a day to eating three meals a day. That helped a ton. But then we added a Erin's like, yes. Um, but then we added in some really cool peptides like the cloth stack. So that's G H K C U, copper peptide, BPC157, TB500, and KPV. And I got the coolest message from her like three months into the program. She was like, I was on one of my calls and my client asked if I got an extensions. And she's like, Nope, I'm just on the peptide bus. And she's like, it's funny because I could see it, but now other people can see it too. And I like that one because it's not just weight loss. It's like, you know, how how else can you kind of optimize? How else can you feel good on some of these peptides besides just thinking about like, can I get skinnier? You know, Julia didn't need it, didn't want it, and and peptides worked really well for her.

SPEAKER_01

Yeah, there are those signs of health like your hair, nails, your cycle. I mean, all of these things are signals of health and how you're dysfunctionally doing in general. I'm also curious, is there any others that we haven't talked about that you see come up a lot with women specifically?

SPEAKER_00

I think. I mean, well, we did just mention kind of the closed stack, right? So this is the GHKCU copper peptide formulated in a concentration, like a solution with KPV, anti-inflammatory peptide, with BPC157, which helps the gut and also helps inflammation with TB500, which also helps repair an inflammation. And so this one, I will tell you, I didn't used to recommend it because actually, okay, I I am a big nerd. I did my master's thesis on copper, all right? I know that's nerdy, but I will tell you that because they're copper can really degrade other molecules, right? And so when I learned that the close stack had GHKCU in it, I was like, I don't really think people should be taking that because it's gonna break down all those other peptides. It's gonna be like, you know, like you're only taking GHKCU. And so when I started working with this telehealth compounding company and they were like, oh, we're coming out of the close stack, I was like, well, I'm not recommending that to my clients because it's gonna degrade. And so I was able to actually talk to our chief pharmacist and ask him, um, what are we doing to make sure that, you know, this copper isn't degrading the other peptides? And he sent the entire, you know, um, like outline of what the company had done, what the pharmacy had done to keep the pH stable at 6.5 balance at 6.5 to make sure that none of those peptides are being degraded in the close stack. So once I had that science, I was like, oh, hell yeah, this is awesome. So I'm on it. My 19-year-old daughter is on it, my husband is on it, many of my clients are on it. And that close stack, again, can be super helpful for gut health, for recovery. Um, I've definitely noticed a difference. I've got this like persistent, you know, elbow or um shoulder issue because I'm 43 and I like to lift weights and I'm just like old and it hurts a lot. And so I've been really intentional with my cloth stack and I'm actually injecting it into the back of my arm instead of into my abdomen and just trying to get it to the site where it can heal. And lo and behold, I like I'm not kidding. Like my my shoulder is feeling better than it has felt in a couple of years. And I hear story after story after story of my clients dealing with tennis elbow, dealing with um, you know, inflammatory issues of like joints, where BPC 157 TB500 have really, really helped reduce inflammation. And so I think the closed stack, while it can be a little bit, you know, expensive, I think it's completely worth it, completely worth it to um, you know, add to your stack.

SPEAKER_01

And I keep hearing stack. So the stack just means when you're putting combining them into one injection.

SPEAKER_00

Yep. Well, no, not one injection, but just like injecting it at the same time. So we we would say just for you know, to make sure that again, one peptide's not degrading another, one peptide isn't getting into another peptide vial and kind of like um, you know, causing an issue with with dilution or um contamination. You don't ever want to inject the same like with the same needle, right? So you wouldn't pull multiple peptides into one needle, but you can inject multiple peptides in a day. I do. Erin, I wish I could show you like me and my husband's peptide needle drawer. There's like 500 peptide needles in there because every time we order a prescription, the pharmacy sends us these needles. And I'm like, wow, this just looks bad, but we feel great. So you can use multiple needles to take multiple peptides in the same day, you know, which we do. But yeah, a stack would just mean like, how can we make something, you know, that's working maybe work a little bit better. And not everybody has to stack, but some of the more popular ones are a GLP one to lose weight, plus a peptide called MOTS C, which is a metabolic peptide. They call it exercise in a bottle. It's not really, it's not gonna make you like fit if you're sitting on the couch. But if you're on a GLP1, your foundations are locked in, and you add MOT C, it can help your metabolic, you know, rate be a little bit higher, can help you burn fat a little bit easier by regulating your glucose. Um, it's a true metabolic peptide. So that's one stack that we really like. The other stack we like, especially for midlife women, is GLP1 plus tesimeralin and KPV. So GLP1 to lose weight and manage cravings, and then tesimeralin for belly fat and KPV to not have you like have that inflammatory water weight. So those are probably two of my favorites. And then um just the closed stack in one bottle is definitely one of my favorites. And since that's already compounded as four peptides in one bottle, you don't have to, you can draw it in the same needle, which is like chef's kiss.

SPEAKER_01

Yes, okay, because that's what I was thinking before, but the true stack just means like you're combining them and doing them at the same time.

SPEAKER_00

Yep.

SPEAKER_01

Yep. Okay, got it. Well, as we come to the end, one question I also wanted to ask was what is one thing that you think people get wrong with peptides that you wish women knew?

SPEAKER_00

I do wish women knew that they don't have to go to like sketchy websites to get peptides. Like, as we just had the patients. Oh, yeah, please know. Yeah, yeah, don't do it. Like, I mean, you wouldn't buy your magnesium like off this random peptide like site online, you know, you wouldn't buy your kids like formula from like a random sketchy site online, and people are just buying like peptides from the weirdest sites, or even like doctors who are using research peptides. They're literally say for research only, they're not using uh compounding pharmacy. I'm not saying everyone has to. I know people are gonna buy research peptides, but I will say, as again, the PCAC met last week, we're moving a class of peptides off class two onto class one, um, so that now compounding pharmacies can legally write a lot of these peptides like MOT C and KPV. You, you, you aren't spending that much more money for physician oversight than you are on research peptides. You get a doctor, ta-da. You get like a lot of compounding pharmacies like provide you the syringes and like how to take the peptide, where like research peptides won't do that. Research peptides, you have to compound your own, you have to figure out your own dosing. Pharmacies will give you the dose, they'll constitute it for you. Like, it's not quite apples to apples, and some people like don't have access or they just want to save money, you know. I get that too. But if you have a better option, I would say use the better option. There's no shame in like using a doctor for your peptides, you know, you'll you'll be happy in the long run.

SPEAKER_01

I just think of Amazon and all the access to crazy things that we can order instantly. And so it becomes a little second nature for us to be able to, oh yeah, like I can get something and you just assume quality. I'm going through Amazon. It's like that is a bad assumption. Like you have no idea who that supplier is that you potentially are buying from unless you research it and verify. Like, I think so many of us also with beauty products, we just we're like, oh, it like that video looked great. Look how long eyelashes are. Well, careful. Do you know what's in that mascara bottle before you go whipping that on your eyeballs? Like, where is it coming from? What's in that bottle? You can't just trust marketing. So I think it is very much do your research, go through trusted parties, know what you're doing as you get into it to reap all of these awesome benefits.

SPEAKER_00

100%. 100%.

SPEAKER_01

Well, there anything that we didn't touch on that you wish we would have?

SPEAKER_00

I think I think we ran the gamut, just making sure that before women get into peptides, that they really just have their foundations dialed in, right? And then, you know, knowing that peptides are you when used correctly, right? And when used in a fairly healthy body can be really life-changing for women in midlife. They're safe, they're efficacious, they're well studied, especially the GLP ones. Um, you know, do your due diligence, use a doctor or a compounding pharmacy. But I think it I just think that we are living in this amazing time, seeing this like, you know, medical and technological revolution that really is going to change the trajectory of women's health. And man, I'm here for it.

SPEAKER_01

Amen. Jennifer, thank you so much for coming on. If people wanted to learn more about you and your podcast or company, where can they go?

SPEAKER_00

Erin, thank you so much for having me. I had so much fun getting to chat with you today. So thank you for the invitation. And yeah, I am I'm on Instagram all the time at Jennifer Woodward Nutrition. My website is Jenniferwoodwardnutrition.com. Um, so yeah, love to chat with anybody if they have questions on peptides or hormones. Awesome. Thank you again.

SPEAKER_01

Thanks, Erin. Thanks for listening to another episode of Find Your Fuel. If you enjoyed the show and want to support us, please leave a comment or review. And before we go, I have to give you the obligatory medical and legal disclaimer. This podcast is for informational and educational purposes only. The advice and recommendations we discuss are not intended as medical advice and do not replace the treatment or care of a physician or any other primary health care provider. Using the information shared today does not create a doctor-patient relationship and it should not be used to diagnose or treat any health problem. Always consult with a qualified healthcare professional before making changes to your diet, exercise routine, or medications. The use of any information provided is solely at your own risk. So, in a nutshell, let's be smart and remember these stories and conversations are for educational purposes only to help other women find the fuel to live their best lives. We'll see you in the next episode.