Unraveling Glucose and Insulin: Easy-to-Understand Insights

🎙️Your Genes by Design Podcast-Episode 2

Glucose and insulin come up often in health conversations, but many of us were never really taught how they work together. Once you understand that connection, things like mid-afternoon crashes and sudden cravings start to make a lot more sense.

In this episode, we’ll look at the glucose–insulin relationship in simple, practical terms—and how genes like TCF7L2, FADS1, and PPARGC1A can influence how your body handles carbs, fats, and energy after 45.

What You’ll Learn

* The simple relationship between glucose and insulin—and why it drives energy, focus, and cravings

* How insulin resistance begins and what early signs look like

* The role of TCF7L2, FADS1, and PPARGC1A in carbohydrate tolerance, fat metabolism, and energy stability

* Why two people can eat the same meal and feel completely different

🩸 Your Next Step Toward Balance

If you’ve ever felt your energy crash a few hours after eating, here are small shifts that help your body stay responsive:

1️⃣ Pair carbs with protein or healthy fats to steady glucose.

2️⃣ Move a little after meals — even a short walk helps insulin do its job.

3️⃣ Prioritize sleep and lower stress to keep your cells sensitive to insulin.

4️⃣ Notice patterns — when do you feel clear, focused, or foggy? Those clues show how your system is responding.

Understanding your body’s glucose–insulin rhythm isn’t about restriction — it’s about awareness. The more you notice, the easier it is to make choices that keep your energy steady.

The Precision Piece

If you’ve ever felt like you’re doing everything “right” but still struggle with energy dips or cravings, your genes may hold the missing key.

Knowing your variants for TCF7L2, FADS1, and PPARGC1A can bring clarity to what your body needs most—whether that’s balancing carbs differently, emphasizing omega-3 fats, or supporting mitochondrial function for steadier energy.

That insight isn’t about restriction—it’s about precision. Understanding your design helps you make decisions that actually work for your body, not against it.

Know someone 45+ who’d benefit? Share this.

Chapters

• 0:32 Intro (host)
• 1:20 Why glucose matters for energy & mood
• 2:15 How insulin works (“the key that unlocks the door”)
• 3:10 What happens with insulin resistance
• 4:00 Genes that influence your response
• 5:00 Real-life example (bagel vs. balanced breakfast)
• 6:00 Takeaway & closing

Transcript

In this 7-minute episode, we explore how glucose and insulin shape midlife energy — and how genes like TCF7L2, FADS1, and PPARGC1A influence your body’s unique response.
💬 Full transcript →