Your Genes by Design

Oxygenation: The Missing Link Between Energy, Glucose, and Genes

Your genes explain tendencies, not destiny. Season 1 Episode 3

 Feeling steady energy isn’t luck — it’s the result of how efficiently our cells use oxygen to turn fuel into power. In this episode, we trace the path from breath to mitochondria to blood sugar, showing how oxygenation influences glucose and insulin balance after 45. 

What You’ll Learn

  • How oxygen use determines whether glucose becomes clean energy or stored fuel
  • Why mitochondrial health is the missing link between insulin sensitivity and stamina
  • The roles of PPARGC1A, SOD2, and NOS3 in energy production, antioxidant defense, and blood flow
  • How estrogen and thyroid changes after 45 affect oxygen delivery and glucose balance
  • Simple ways to support oxygenation through breathing, movement, and nutrition

Your Next Step Toward Steadier Energy
If your energy feels unpredictable — clear one day and flat the next — small shifts can help. Move often, breathe through your nose, focus on nutrients that fuel mitochondria, and protect your sleep window. When oxygen delivery improves, glucose burns cleanly, energy steadies, and recovery feels easier.

The Precision Piece
If you’ve noticed slower recovery, afternoon fatigue, or brain fog that coffee can’t fix, your genes may reveal why. Variants in PPARGC1A, SOD2, and NOS3 affect how efficiently your cells use oxygen and handle oxidative stress. Understanding those patterns isn’t about perfection — it’s about precision. The more you know how your body is wired, the easier it becomes to build steadier energy and clearer focus — by design.

In this 5-minute episode, we explore how oxygenation influences glucose and insulin balance — and how genes like PPARGC1A, SOD2, and NOS3 shape energy, recovery, and focus after 45.
💬 Full transcript →